ChemInform Abstract: An Efficient Synthesis of γ-Amino-β-ketoalkylphosphonates from α-Amino Acids.
Abstract
The amino acid esters (I) react with the phosphonates (II) to give the ketophosphonates (III) which are split by trimethylsilyl bromide to yield the γ-amino-β-ketophosphonates (IV).
ChemInform Abstract
The amino acid esters (I) react with the phosphonates (II) to give the ketophosphonates (III) which are split by trimethylsilyl bromide to yield the γ-amino-β-ketophosphonates (IV). (IR-, NMR-data).