Volume 18, Issue 35
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of Pyrrolo(2,1-c) (1,4)benzothiazines by Annellation of 3-Alkoxycarbonylmethylene-4H-1,4-benzothiazines (β-Enamine Esters) with Dimethyl Acetylenedicarboxylate.

G. TRAPANI

G. TRAPANI

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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A. REHO

A. REHO

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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A. LATROFA

A. LATROFA

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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F. MORLACCHI

F. MORLACCHI

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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G. LISO

G. LISO

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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F. STASI

F. STASI

Dip. Farm.-chim., Univ. Bari, 70126 Bari, Italy

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First published: September 1, 1987

Abstract

The annellation of the benzothiazines (I) with the acetylene (II) proceeds via the Michael adducts (III) to give the pyrrolobenzothiazines (IV); both the latter can be converted to the pyrrolobenzothiazines (V).

ChemInform Abstract

The annellation of the benzothiazines (I) with the acetylene (II) proceeds via the Michael adducts (III) to give the pyrrolobenzothiazines (IV); both the latter can be converted to the pyrrolobenzothiazines (V). The X-ray structure of (IVa) (space group P1, Z=2) is reported.

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