Volume 18, Issue 35
Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Experimental Antitumor Activities of 6-Alkyl(or Aryl)thio-5-deazapteridines.

F. POCHAT

F. POCHAT

Lab. Synth. Org., Univ. Rennes I, 35042 Rennes, Fr.

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F. LAVELLE

F. LAVELLE

Lab. Synth. Org., Univ. Rennes I, 35042 Rennes, Fr.

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C. FIZAMES

C. FIZAMES

Lab. Synth. Org., Univ. Rennes I, 35042 Rennes, Fr.

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A. ZERIAL

A. ZERIAL

Lab. Synth. Org., Univ. Rennes I, 35042 Rennes, Fr.

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First published: September 1, 1987

Abstract

The title compounds (III) are synthesized as described in the scheme and tested against leukemia cells.

ChemInform Abstract

The title compounds (III) are synthesized as described in the scheme and tested against leukemia cells. Whereas the 6-arylthio derivative (IIIa) is active, the alkylthio derivatives (IIIb)-(IIId) do not exhibit any effects.

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