ChemInform Abstract: Synthesis and Experimental Antitumor Activities of 6-Alkyl(or Aryl)thio-5-deazapteridines.
Abstract
The title compounds (III) are synthesized as described in the scheme and tested against leukemia cells.
ChemInform Abstract
The title compounds (III) are synthesized as described in the scheme and tested against leukemia cells. Whereas the 6-arylthio derivative (IIIa) is active, the alkylthio derivatives (IIIb)-(IIId) do not exhibit any effects.