Heterocyclic Compounds
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ChemInform Abstract: Regioselective Alkylation of 3-Substituted 3-Sulfolenes.
First published: June 16, 1987
Abstract
The anions, formed from the sulfolenes (Ia) and (Ib) by treatment with butyllithium, are methylated in 2-position to yield the sulfolenes (IIa) and (IIb).
ChemInform Abstract
The anions, formed from the sulfolenes (Ia) and (Ib) by treatment with butyllithium, are methylated in 2-position to yield the sulfolenes (IIa) and (IIb). On the other hand, anions derived from (Ic) yield the 5-methylated products (IIIc). Similar results are obtained using lithium hexamethyldisilazide as a base. (IR-, MS-, 1H-NMR-data).
