ChemInform Abstract: Calcium in Liquid Ammonia for the Reduction of Benzyl Ethers. Mechanistic Clues Derived from Chemoselectivity Studies.
Abstract
The benzylic ethers (I) are cleaved by calcium in liquid ammonia to give the corresponding alcohols (II).
ChemInform Abstract
The benzylic ethers (I) are cleaved by calcium in liquid ammonia to give the corresponding alcohols (II). This reagent is more selective than lithium in liquid ammonia as is proved by the reduction of (III) which yields different ratios of (IV) and (V). (Mechanism).