Frontispiece: In Situ Cyclization of Native Proteins: Structure-Based Design of a Bicyclic Enzyme

Dr. Marta Pelay-Gimeno

Department of Chemistry & Pharmaceutical Sciences, VU University Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands

Dr. Tanja Bange

Department of Mechanistic Cell Biology, Max-Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, 44227 Dortmund, Germany

Department for Systems Chronobiology, LMU Munich, Goethe-Str. 31, 80336 Munich, Germany

Dr. Sven Hennig

Department of Chemistry & Pharmaceutical Sciences, VU University Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands

Corresponding Author

Prof. Dr. Tom N. Grossmann

• [email protected]

• orcid.org/0000-0003-0179-4116

Department of Chemistry & Pharmaceutical Sciences, VU University Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands