Chapter 14
The Role of MGF and Other IGF-I Splice Variants in Muscle Maintenance and Hypertrophy
Geoffrey Goldspink,
Shi Yu Yang,
Mahjabeen Hameed,
Geoffrey Goldspink
Search for more papers by this authorShi Yu Yang
Search for more papers by this authorMahjabeen Hameed
Search for more papers by this authorGeoffrey Goldspink,
Shi Yu Yang,
Mahjabeen Hameed,
Geoffrey Goldspink
Search for more papers by this authorShi Yu Yang
Search for more papers by this authorMahjabeen Hameed
Search for more papers by this authorBook Editor(s):William J. Kraemer,
Alan D. Rogol,
William J. Kraemer
Search for more papers by this authorAlan D. Rogol
Search for more papers by this authorFirst published: 01 January 2005
Summary
This chapter contains section titled:
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Introduction
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Growth hormone-IGF-I axis
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Expression of IGF-I splice variants in muscle
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Mechano growth factor
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Systemic IGF-I is produced by active muscle
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The structure of IGF-I
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Receptors mediate the cellular effects of IGF-I
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IGF-I binding proteins
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Biological action of the IGF-I splice variants
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Genetic manipulation of IGF-I in muscle
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Gene transfer of the different IGF-I splice variants
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IGF-I signaling pathways in muscle hypertrophy
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IGF-I and sarcopenia
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Mechano growth factor, satellite cells and muscle damage
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Summary
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Acknowledgments
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References
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