Volume 10, Issue 6 pp. 526-528
Research Article

Hypolipidaemic Activity of Ficus carica Leaf Extract in Streptozotocin-diabetic Rats

E. Dominguez

E. Dominguez

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, Spain

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J. R. Canal

J. R. Canal

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, Spain

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M. D. Torres

M. D. Torres

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, Spain

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J. E. Campillo

J. E. Campillo

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, Spain

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C. Perez

Corresponding Author

C. Perez

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, Spain

Department of Fisiología, Faculty of Medicine, University of Extremadura, Avda de Elvas s/n, 06071 Badajoz, SpainSearch for more papers by this author

Abstract

A decoction of Ficus carica significantly lowered plasma triglyceride levels in rats with insulin-dependent diabetes (streptozotocin 80 mg/kg body weight) when it was administered orally (357±206 mg/dL before administration and 81±81 mg/dL 3 weeks after administration, p<0.01, n=11). The plasma triglyceride levels in diabetic rats were also lower when the Gicus carica extract was administered intraperitoneally (608±391 mg/dL before administration; 444±310 mg/dL 90 min after administration; and 106±129 mg/dL 48 h after administration; p<0.005, n=7). The cholesterolaemia remained unchanged.

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