Current Trends in Implantable Left Ventricular Assist Devices
This article is part of Special Issue:
Jens Garbade,
Hartmuth B. Bittner,
Markus J. Barten,
Friedrich-Wilhelm Mohr,
Corresponding Author
Jens Garbade
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorHartmuth B. Bittner
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorMarkus J. Barten
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorFriedrich-Wilhelm Mohr
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorJens Garbade,
Hartmuth B. Bittner,
Markus J. Barten,
Friedrich-Wilhelm Mohr,
Corresponding Author
Jens Garbade
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorHartmuth B. Bittner
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorMarkus J. Barten
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorFriedrich-Wilhelm Mohr
Department of Cardiac Surgery, Leipzig Heart Center, University of Leipzig, Struempellstraße 39, 04289 Leipzig, Germany uni-leipzig.de
Search for more papers by this authorAcademic Editor: H. O. Ventura
Abstract
The shortage of appropriate donor organs and the expanding pool of patients waiting for heart transplantation have led to growing interest in alternative strategies, particularly in mechanical circulatory support. Improved results and the increased applicability and durability with left ventricular assist devices (LVADs) have enhanced this treatment option available for end-stage heart failure patients. Moreover, outcome with newer pumps have evolved to destination therapy for such patients. Currently, results using nonpulsatile continuous flow pumps document the evolution in outcomes following destination therapy achieved subsequent to the landmark Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure Trial (REMATCH), as well as the outcome of pulsatile designed second-generation LVADs. This review describes the currently available types of LVADs, their clinical use and outcomes, and focuses on the patient selection process.
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