Volume 2025, Issue 1 1902285
Research Article
Open Access

MultiResFF-Net: Multilevel Residual Block-Based Lightweight Feature Fused Network With Attention for Gastrointestinal Disease Diagnosis

Sohaib Asif

Sohaib Asif

Taizhou Key Laboratory of Minimally Invasive Interventional Therapy & Artificial Intelligence , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

Center of Intelligent Diagnosis and Therapy (Taizhou) , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Taizhou , Zhejiang, 317502 , China , cas.cn

Wenling Institute of Big Data and Artificial Intelligence in Medicine , Taizhou , Zhejiang, 317502 , China

Department of Diagnostic Ultrasound Imaging & Interventional Therapy , Zhejiang Cancer Hospital , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Hangzhou , Zhejiang, 310022 , China , cas.cn

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Yajun Ying

Yajun Ying

Department of Pathology , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

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Tingting Qian

Tingting Qian

Department of Diagnostic Ultrasound Imaging & Interventional Therapy , Zhejiang Cancer Hospital , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Hangzhou , Zhejiang, 310022 , China , cas.cn

Graduate School , The Second Clinical Medical College of Zhejiang Chinese Medical University , Hangzhou , Zhejiang, 310014 , China , zcmu.edu.cn

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Jun Yao

Jun Yao

Department of Surgical Oncology , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

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Jinjie Qu

Jinjie Qu

Department of Surgical Oncology , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

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Vicky Yang Wang

Vicky Yang Wang

Center of Intelligent Diagnosis and Therapy (Taizhou) , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Taizhou , Zhejiang, 317502 , China , cas.cn

Wenling Institute of Big Data and Artificial Intelligence in Medicine , Taizhou , Zhejiang, 317502 , China

Department of Diagnostic Ultrasound Imaging & Interventional Therapy , Zhejiang Cancer Hospital , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Hangzhou , Zhejiang, 310022 , China , cas.cn

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Rongbiao Ying

Corresponding Author

Rongbiao Ying

Department of Surgical Oncology , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

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Dong Xu

Corresponding Author

Dong Xu

Taizhou Key Laboratory of Minimally Invasive Interventional Therapy & Artificial Intelligence , Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) , Taizhou , Zhejiang, 317502 , China

Center of Intelligent Diagnosis and Therapy (Taizhou) , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Taizhou , Zhejiang, 317502 , China , cas.cn

Wenling Institute of Big Data and Artificial Intelligence in Medicine , Taizhou , Zhejiang, 317502 , China

Department of Diagnostic Ultrasound Imaging & Interventional Therapy , Zhejiang Cancer Hospital , Hangzhou Institute of Medicine (HIM) , Chinese Academy of Sciences , Hangzhou , Zhejiang, 310022 , China , cas.cn

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First published: 15 April 2025
Academic Editor: Mohamadreza (Mohammad) Khosravi

Abstract

Accurate detection of gastrointestinal (GI) diseases is crucial due to their high prevalence. Screening is often inefficient with existing methods, and the complexity of medical images challenges single-model approaches. Leveraging diverse model features can improve accuracy and simplify detection. In this study, we introduce a novel deep learning model tailored for the diagnosis of GI diseases through the analysis of endoscopy images. This innovative model, named MultiResFF-Net, employs a multilevel residual block-based feature fusion network. The key strategy involves the integration of features from truncated DenseNet121 and MobileNet architectures. This fusion not only optimizes the model’s diagnostic performance but also strategically minimizes complexity and computational demands, making MultiResFF-Net a valuable tool for efficient and accurate disease diagnosis in GI endoscopy images. A pivotal component enhancing the model’s performance is the introduction of the Modified MultiRes-Block (MMRes-Block) and the Convolutional Block Attention Module (CBAM). The MMRes-Block, a customized residual learning component, optimally handles fused features at the endpoint of both models, fostering richer feature sets without escalating parameters. Simultaneously, the CBAM ensures dynamic recalibration of feature maps, emphasizing relevant channels and spatial locations. This dual incorporation significantly reduces overfitting, augments precision, and refines the feature extraction process. Extensive evaluations on three diverse datasets—endoscopic images, GastroVision data, and histopathological images—demonstrate exceptional accuracy of 99.37%, 97.47%, and 99.80%, respectively. Notably, MultiResFF-Net achieves superior efficiency, requiring only 2.22 MFLOPS and 0.47 million parameters, outperforming state-of-the-art models in both accuracy and cost-effectiveness. These results establish MultiResFF-Net as a robust and practical diagnostic tool for GI disease detection.

Conflicts of Interest

The authors declare no conflicts of interest.

Data Availability Statement

The data that support the findings of this study are available from the corresponding authors upon reasonable request.

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