Volume 2014, Issue 1 804917
Case Report
Open Access

Successful Use of Extracorporeal Membrane Oxygenation for Respiratory Failure Caused by Mediastinal Precursor T Lymphoblastic Lymphoma

Masafumi Oto

Corresponding Author

Masafumi Oto

Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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Kyoko Inadomi

Kyoko Inadomi

Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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Toshiyuki Chosa

Toshiyuki Chosa

Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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Shima Uneda

Shima Uneda

Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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Soichi Uekihara

Soichi Uekihara

Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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Minoru Yoshida

Minoru Yoshida

Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan

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First published: 17 December 2014
Citations: 12
Academic Editor: Gottfried J. Locker

Abstract

Precursor T lymphoblastic lymphoma (T-LBL) often manifests as a mediastinal mass sometimes compressing vital structures like vessels or large airways. This case was a 40-year-old male who developed T-LBL presenting as respiratory failure caused by mediastinal T-LBL. He presented with persistent life threatening hypoxia despite tracheal intubation. We successfully managed this respiratory failure using venovenous (VV) ECMO. Induction chemotherapy was started after stabilizing oxygenation and the mediastinal lesion shrank rapidly. Respiratory failure caused by compression of the central airway by tumor is an oncologic emergency. VV ECMO may be an effective way to manage this type of respiratory failure as a bridge to chemotherapy.

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