Volume 2014, Issue 1 641989
Case Report
Open Access

Lepra Reaction with Lucio Phenomenon Mimicking Cutaneous Vasculitis

Durga Prasanna Misra

Corresponding Author

Durga Prasanna Misra

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Jyoti Ranjan Parida

Jyoti Ranjan Parida

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Abhra Chandra Chowdhury

Abhra Chandra Chowdhury

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Krushna Chandra Pani

Krushna Chandra Pani

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Niraj Kumari

Niraj Kumari

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Narendra Krishnani

Narendra Krishnani

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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Vikas Agarwal

Vikas Agarwal

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India sgpgi.ac.in

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First published: 17 December 2014
Citations: 9
Academic Editor: Rajni Rani

Abstract

Leprosy is a disease typically found in the tropics. Patients with leprosy can have varying presentation with constitutional symptoms, joint pains, skin nodules, and rarely a vasculitis-like picture with skin ulcers and neuropathy. We present a young lady who presented with the rare manifestation of skin infarcts mimicking cutaneous vasculitis, diagnosed on histopathology to have Lucio phenomenon on a background of lepromatous leprosy. With increasing migration and widespread use of biologic response modifiers, clinicians all over the world need to be aware of various presentations of leprosy as well as needing to keep an open mind while considering the differential diagnoses of vasculitis.

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