5-ASA Therapy in Solitary Rectal Ulcer Syndrome. Report of Three Patients

Solitary rectal ulcer syndrome (SRUS) is a rare condition which presents typically with a long standing history of constipation, straining, rectal bleeding, mucus discharge and pain on defecation. Three cases of SRUS arc discussed which were all successfully treated with 5-ASA enemas. Complete healing occurred within a few weeks and recurrent ulcers healed just as readily with renewed therapy.