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Efficacy of plasmapheresis for the treatment of pure red blood cell aplasia after allogeneic stem cell transplantation

Corresponding Author

Chiara Maria Dellacasa

SSCVD Trapianto di Cellule Staminali Allogeniche, AOU Cittaà della Salute e della Scienza

Address reprint requests to: Chiara Maria Dellacasa, SSCVD Trapianto di Cellule Staminali Allogeniche, AOU Città Della Salute e Della Scienza, Torino, Italy; e-mail: [email protected].Search for more papers by this author

Stefano D'Ardia,

Stefano D'Ardia

SC Ematologia, AOU Città della Salute e della Scienza

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Bernardino Allione,

Bernardino Allione

SC Ematologia, AOU Città della Salute e della Scienza

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Semra Aydin,

Semra Aydin

SC Ematologia, AOU Città della Salute e della Scienza

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Valter Tassi,

Valter Tassi

SC Banca del Sangue, AOU Città della Salute e della Scienza

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Tiziana Francisci,

Tiziana Francisci

SC Banca del Sangue, AOU Città della Salute e della Scienza

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Clara Pecoraro,

Clara Pecoraro

SC Immunopatologia e Malattie Rare, Ospedale San Giovanni Bosco, Torino, Italy

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Alessandro Busca,

Alessandro Busca

SSCVD Trapianto di Cellule Staminali Allogeniche, AOU Cittaà della Salute e della Scienza

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Chiara Maria Dellacasa,

Corresponding Author

Chiara Maria Dellacasa

SSCVD Trapianto di Cellule Staminali Allogeniche, AOU Cittaà della Salute e della Scienza

Stefano D'Ardia,

Stefano D'Ardia

SC Ematologia, AOU Città della Salute e della Scienza

Search for more papers by this author

Bernardino Allione,

Bernardino Allione

SC Ematologia, AOU Città della Salute e della Scienza

Search for more papers by this author

Semra Aydin,

Semra Aydin

SC Ematologia, AOU Città della Salute e della Scienza

Search for more papers by this author

Valter Tassi,

Valter Tassi

SC Banca del Sangue, AOU Città della Salute e della Scienza

Search for more papers by this author

Tiziana Francisci,

Tiziana Francisci

SC Banca del Sangue, AOU Città della Salute e della Scienza

Search for more papers by this author

Clara Pecoraro,

Clara Pecoraro

SC Immunopatologia e Malattie Rare, Ospedale San Giovanni Bosco, Torino, Italy

Search for more papers by this author

Alessandro Busca,

Alessandro Busca

SSCVD Trapianto di Cellule Staminali Allogeniche, AOU Cittaà della Salute e della Scienza

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First published: 24 September 2015

https://doi.org/10.1111/trf.13269

Citations: 16

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Abstract

BACKGROUND

Pure red blood cell aplasia (PRCA) is a complication of ABO major-incompatible stem cell transplantation, likely due to the persistence of memory B lymphocytes of recipient origin, which produce hemagglutinins against ABO antigens on donor RBCs. At present no standard of care is established for this complication.

CASE REPORT

We report a case of PRCA after allogeneic bone marrow transplantation, successfully treated with plasma exchange (PEX) after failing erythropoietin administration.

RESULTS

The patient fully recovered from RBC aplasia.

CONCLUSION

This case suggests a role for PEX in the treatment of PRCA after allogeneic stem cell transplantation.

REFERENCES

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Citing Literature

Volume55, Issue12

December 2015

Pages 2979-2982

Efficacy of plasmapheresis for the treatment of pure red blood cell aplasia after allogeneic stem cell transplantation

Abstract

BACKGROUND

CASE REPORT

RESULTS

CONCLUSION

REFERENCES

Citing Literature

References

Information

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Efficacy of plasmapheresis for the treatment of pure red blood cell aplasia after allogeneic stem cell transplantation

Abstract

BACKGROUND

CASE REPORT

RESULTS

CONCLUSION

REFERENCES

Citing Literature

References

Related

Information