Volume 56, Issue 1 pp. 125-129
TRANSFUSION PRACTICE

A possible new paradigm? A survey-based assessment of the use of thawed group A plasma for trauma resuscitation in the United States

Nancy M. Dunbar

Corresponding Author

Nancy M. Dunbar

Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Address reprint requests to: Nancy M. Dunbar, MD, One Medical Center Drive, Lebanon, NH 03756-0001; e-mail: [email protected].Search for more papers by this author
Mark H. Yazer

Mark H. Yazer

The Institute for Transfusion Medicine, Pittsburgh, Pennsylvania

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

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on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative

on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative

Biomedical Excellence for Safer Transfusion (BEST) Collaborative, Lebanon, New Hampshire.

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First published: 20 August 2015
Citations: 33

Abstract

BACKGROUND

Although evidence supporting this practice is limited, some centers use thawed group A plasma for the initial resuscitation of trauma patients.

STUDY DESIGN AND METHODS

To better understand the current use of plasma in trauma resuscitation, a survey was developed, validated, and distributed via e-mail to 121 American trauma centers.

RESULTS

A total of 61 responses were received. Most were from Level 1 trauma centers (56/61, 92%) in urban settings (47/61, 77%). Virtually all centers reported maintaining A thawed plasma inventory (59/61, 97%). Among the 56 Level 1 trauma center respondents, most keep thawed A immediately available (49/56, 88%) and many use group A plasma for trauma recipients of unknown ABO group (34/49, 69%). Half of the surveyed centers implemented this practice within the past year. The majority do not limit the amount of A plasma that can be administered to a patients of unknown ABO group (21/34, 62%), and most do not titer for anti-B (27/34, 79%).

CONCLUSION

The majority of Level 1 trauma centers maintain thawed plasma inventories and use group A plasma for trauma recipients of unknown ABO group. Most centers do not limit the amount of group A plasma used in this situation or titer the anti-B.

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