Association between epilepsy and oral maxillofacial trauma: A systematic review and meta-analysis
Saulo Gabriel Moreira Falci DDS, MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorCorresponding Author
Lucas Duarte-Rodrigues DDS, MSc
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Correspondence
Lucas Duarte-Rodrigues, Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Diamantina/MG, Brazil. Zip code: 39100-000.
Email: [email protected]
Search for more papers by this authorEdnele Fabyene Primo-Miranda DDS, MSc
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorPatrícia Furtado Gonçalves DDS, MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorEndi Lanza Galvão MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorSaulo Gabriel Moreira Falci DDS, MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorCorresponding Author
Lucas Duarte-Rodrigues DDS, MSc
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Correspondence
Lucas Duarte-Rodrigues, Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Diamantina/MG, Brazil. Zip code: 39100-000.
Email: [email protected]
Search for more papers by this authorEdnele Fabyene Primo-Miranda DDS, MSc
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorPatrícia Furtado Gonçalves DDS, MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorEndi Lanza Galvão MSc, PhD
Department of Dentistry, Postgraduate Program in Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil
Search for more papers by this authorAbstract
A systematic literature search was conducted (through April 2017), using Web of Science, PubMed and Virtual Health Library, manual reference list, and grey literature searches. The quality of the studies was evaluated using the Newcastle-Ottawa Quality Assessment Scale. The meta-analysis was performed using R software. A total of 30 studies was included in this review. From a total of 25 studies included in the meta-analysis, the prevalence of oral and maxillofacial injuries among epileptic subjects was 19%. Among the epileptic patients who suffered some type of injury due to epileptic seizures, 52% had facial soft tissue injuries (95%CI: 28-75%), 18% suffered dental trauma (95%CI: 11-29%), and 12% (95%CI: 4-28%) suffered maxillofacial fractures. Epileptic patients were more likely to have oral and maxillofacial injuries than healthy individuals (OR: 5.22, 95%CI: 2.84-9.36) and subjects with psychogenic nonepileptic seizures (OR: 2.77, 95%CI: 1.28-5.99), but not than patients with special needs (OR: 2.45,95%CI: 0.95-6.31).
CONFLICT OF INTEREST
The authors whose names are listed immediately below certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or nonfinancial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.
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