Safety and diagnostic performance of pulmonologists performing electromagnetic guided percutaneous lung biopsy (SPiNperc)
Christopher Mallow
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorHans Lee
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCatherine Oberg
Division of Pulmonary and Critical Care Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, USA
Search for more papers by this authorJeffrey Thiboutot
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorJason Akulian
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Search for more papers by this authorAllen C. Burks
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Search for more papers by this authorBranden Luna
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorSadia Benzaquen
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Search for more papers by this authorHitesh Batra
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
Search for more papers by this authorJose Cardenas-Garcia
Division of Pulmonary and Critical Care Medicine, University of Michigan School, Ann Arbor, MI, USA
Search for more papers by this authorJennifer Toth
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA
Search for more papers by this authorJay Heidecker
Division of Pulmonary Medicine, Birmingham Pulmonary Group, Birmingham, AL, USA
Search for more papers by this authorAdam Belanger
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Search for more papers by this authorJason McClune
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA
Search for more papers by this authorUmar Osman
Division of Pulmonary and Critical Care Medicine, Memorial Health System, Marietta, OH, USA
Search for more papers by this authorVenkatesh Lakshminarayanan
Division of Pulmonary and Critical Care Medicine, Pulmonary and Critical Care of Atlanta, Atlanta, GA, USA
Search for more papers by this authorNicholas Pastis
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorGerard Silvestri
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorAlexander Chen
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Search for more papers by this authorCorresponding Author
Lonny Yarmus
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Correspondence: Lonny Yarmus, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 1830 East Monument Street, 5th Floor, Baltimore, MD 21287, USA. Email: [email protected]Search for more papers by this authorChristopher Mallow
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorHans Lee
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorCatherine Oberg
Division of Pulmonary and Critical Care Medicine, Ichan School of Medicine at Mount Sinai, New York, NY, USA
Search for more papers by this authorJeffrey Thiboutot
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Search for more papers by this authorJason Akulian
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Search for more papers by this authorAllen C. Burks
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Search for more papers by this authorBranden Luna
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorSadia Benzaquen
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Search for more papers by this authorHitesh Batra
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
Search for more papers by this authorJose Cardenas-Garcia
Division of Pulmonary and Critical Care Medicine, University of Michigan School, Ann Arbor, MI, USA
Search for more papers by this authorJennifer Toth
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA
Search for more papers by this authorJay Heidecker
Division of Pulmonary Medicine, Birmingham Pulmonary Group, Birmingham, AL, USA
Search for more papers by this authorAdam Belanger
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Search for more papers by this authorJason McClune
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA
Search for more papers by this authorUmar Osman
Division of Pulmonary and Critical Care Medicine, Memorial Health System, Marietta, OH, USA
Search for more papers by this authorVenkatesh Lakshminarayanan
Division of Pulmonary and Critical Care Medicine, Pulmonary and Critical Care of Atlanta, Atlanta, GA, USA
Search for more papers by this authorNicholas Pastis
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorGerard Silvestri
Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
Search for more papers by this authorAlexander Chen
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, USA
Search for more papers by this authorCorresponding Author
Lonny Yarmus
Section of Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Correspondence: Lonny Yarmus, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 1830 East Monument Street, 5th Floor, Baltimore, MD 21287, USA. Email: [email protected]Search for more papers by this authorABSTRACT
Background and objective
Percutaneous lung biopsy for diagnostic sampling of peripheral lung nodules has been widely performed by interventional radiologists under computed tomography (CT) guidance. New technology allows pulmonologists to perform percutaneous lung biopsies using electromagnetic (EM) guided technology. With the adoption of this new technique, the safety, feasibility and diagnostic yield need to be explored. The goal of this study was to determine the safety, feasibility and diagnostic yield of EM-guided percutaneous lung biopsy performed by pulmonologists.
Methods
We conducted a retrospective, multicentre study of 129 EM-guided percutaneous lung biopsies that occurred between November 2013 and March 2017. The study consisted of seven academic and three community medical centres.
Results
The average age of participants was 65.6 years, BMI was 26.3 and 50.4% were females. The majority of lesions were in the right upper lobe (37.2%) and left upper lobe (31.8%). The mean size of the lesions was 27.31 mm and the average distance from the pleura was 13.2 mm. Practitioners averaged two fine-needle aspirates and five core biopsies per procedure. There were 23 (17.8%) pneumothoraces, of which 16 (12.4%) received small-bore chest tube placement. The diagnostic yield of percutaneous lung biopsy was 73.7%. When EM-guided bronchoscopic sampling was also performed during the same procedural encounter, the overall diagnostic yield increased to 81.1%.
Conclusion
In this large multicentred series, the use of EM guidance for percutaneous lung biopsies was safe and feasible, with acceptable diagnostic yield in the hands of pulmonologists. A prospective multicentre trial to validate these findings is currently underway (NCT03338049).
Supporting Information
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resp13471-sup-0001-VisualAbstract.pptxPowerPoint 2007 presentation , 296.9 KB |
Visual Abstract Electromagnetic guided transthoracic needle biopsy is safe, feasible and has high diagnostic yield |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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