Volume 24, Issue 2 pp. 182-194

ORIGINAL ARTICLE

Clinical study on low-frequency repetitive transcranial magnetic stimulation for the treatment of walking dysfunction following stroke through three-dimensional gait analysis

Xinxin Shu,

Xinxin Shu

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

Xinxin Shu and Hong Yu contributed equally to this work.

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Hong Yu,

Corresponding Author

Hong Yu

[email protected]

orcid.org/0009-0005-5015-2533

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

Xinxin Shu and Hong Yu contributed equally to this work.

Correspondence: Ms. Hong Yu and Mr. Yuda Zhou, Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, No. 2828, Binsheng Road, Binjiang District, Hang Zhou, 310000, China. Email: [email protected] and [email protected]

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Yuda Zhou,

Corresponding Author

Yuda Zhou

[email protected]

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

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Siwei Zhou,

Siwei Zhou

Department of Elderly Rehabilitation, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

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Bei Chen,

Bei Chen

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

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Xinxin Shu,

Xinxin Shu

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

Xinxin Shu and Hong Yu contributed equally to this work.

Search for more papers by this author

Hong Yu,

Corresponding Author

Hong Yu

[email protected]

orcid.org/0009-0005-5015-2533

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

Xinxin Shu and Hong Yu contributed equally to this work.

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Yuda Zhou,

Corresponding Author

Yuda Zhou

[email protected]

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

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Siwei Zhou,

Siwei Zhou

Department of Elderly Rehabilitation, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

Search for more papers by this author

Bei Chen,

Bei Chen

Rehabilitation Assessment and Treatment Centre, Zhejiang Rehabilitation Medical Centre, Hang Zhou, China

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First published: 02 January 2024

https://doi.org/10.1111/psyg.13058

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Abstract

Background

The recovery of walking capacity is of great significance in stroke rehabilitation. We evaluated changes in post-stroke gait function after low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) treatment.

Methods

Stroke patients were randomly assigned to control (conventional treatment)/LF-rTMS (LF-rTMS treatment based on conventional treatment) groups. Gait spatiotemporal parameters/affected side joint motion angle/affected side dynamic parameters were analyzed by 3D gait analyses. Motor evoked potential (MEP)/central motor conduction time (CMCT) changes were detected. Correlations between MEP latency/CMCT and gait parameters after LF-rTMS were analyzed by Pearson analysis.

Results

The two groups exhibited boosted stride speed/frequency/length, affected side stride length/swing phase percentage/hip/knee/ankle joint plantar flexion angle, and affected side ahead ground reaction force/ upward ground reaction force (AGRF/UGRF)/ankle joint plantar flexion moment, along with reduced affected side gait period/stance phase percentage after treatment, and the LF-rTMS group manifested better efficacy. MEP latency/CMCT of stroke patients treated with LF-rTMS was adversely linked to stride speed, affected side stride length/swing phase percentage/knee flexion angle, AGRF and UGRF, and positively correlated with affected side stance phase percentage.

Conclusion

LF-rTMS significantly improved gait spatiotemporal parameters/affected joint motion angles/neurophysiologic parameters (MEP latency/CMCT) in patients with post-stroke walking dysfunction. MEP latency/CMCT after LF-rTMS treatment were prominently correlated with gait parameters. Relative to the traditional scale assessment, we provided a more accurate, objective and reliable evaluation of the effects of LF-rTMS on lower limb mobility and functional recovery effects in stroke patients from the perspective of 3D gait analysis and neurophysiology, which provided more evidence to support the clinical application of LF-rTMS in post-stroke walking dysfunction treatment.

Open Research

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Volume24, Issue2

March 2024

Pages 182-194

Clinical study on low-frequency repetitive transcranial magnetic stimulation for the treatment of walking dysfunction following stroke through three-dimensional gait analysis

Abstract

Background

Methods

Results

Conclusion

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Information

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Clinical study on low-frequency repetitive transcranial magnetic stimulation for the treatment of walking dysfunction following stroke through three-dimensional gait analysis

Abstract

Background

Methods

Results

Conclusion

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Related

Information