Volume 21, Issue 6 e13005
CASE REPORT

Three relapses after a haploidentical transplantation in a pediatric patient: Cure with no further transplantation

Vedat Uygun

Corresponding Author

Vedat Uygun

Bahçeşehir University, Faculty of Medicine, MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey

Correspondence

Vedat Uygun, Bahçeşehir University, Faculty of Medicine, MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey.

Email: [email protected]

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Hayriye Daloglu

Hayriye Daloglu

MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey

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Seda Öztürkmen

Seda Öztürkmen

MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey

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Gulsun Karasu

Gulsun Karasu

Bahçeşehir University, Faculty of Medicine, MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey

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Akif Yesilipek

Akif Yesilipek

Bahçeşehir University, Faculty of Medicine, MedicalPark Antalya Hospital, Pediatric BMT Unit, Antalya, Turkey

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First published: 13 July 2017

Abstract

Isolated extramedullary relapse (EMR) after hematopoietic stem cell transplantation (HSCT) is a highly fatal condition that creates uncertainty regarding treatment options. Although certain approaches such as repeat HSCT and donor lymphocyte infusion are recommended, we report a patient with acute lymphoblastic leukemia who had three isolated EMRs after HSCT at different locations and at different times that were responsive to local and systemic therapies, without the need for a second transplantation.

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