SHORT COMMUNICATION

Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: A rising concern

Corresponding Author

Lorenzo Azzi

[email protected]

orcid.org/0000-0003-2532-7651

Unit of Oral Medicine and Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Correspondence

Lorenzo Azzi, Department of Medicine and Surgery, University of Insubria, 21100 Varese (Velate), Italy.

Email: [email protected]

Search for more papers by this author

Giulio Carcano,

Giulio Carcano

Unit of General, Emergency and Transplant Surgery, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Daniella Dalla Gasperina,

Daniella Dalla Gasperina

Unit of Infectious and Tropical Diseases, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Fausto Sessa,

Fausto Sessa

Unit of Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Vittorio Maurino,

Vittorio Maurino

Unit of Oral Medicine and Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Andreina Baj,

Andreina Baj

Laboratory of Clinical Microbiology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Lorenzo Azzi,

Corresponding Author

Lorenzo Azzi

[email protected]

orcid.org/0000-0003-2532-7651

Unit of Oral Medicine and Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Correspondence

Lorenzo Azzi, Department of Medicine and Surgery, University of Insubria, 21100 Varese (Velate), Italy.

Email: [email protected]

Search for more papers by this author

Giulio Carcano,

Giulio Carcano

Unit of General, Emergency and Transplant Surgery, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Daniella Dalla Gasperina,

Daniella Dalla Gasperina

Unit of Infectious and Tropical Diseases, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Fausto Sessa,

Fausto Sessa

Unit of Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Vittorio Maurino,

Vittorio Maurino

Unit of Oral Medicine and Pathology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

Andreina Baj,

Andreina Baj

Laboratory of Clinical Microbiology, ASST dei Sette Laghi – Ospedale di Circolo, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Search for more papers by this author

First published: 25 April 2020

https://doi.org/10.1111/odi.13368

Citations: 29

Share a link

Email
Wechat
Bluesky

Abstract

We report two cases of COVID-19 showing negative respiratory swabs but positive salivary samples at the same time. These findings rise the concern about how to manage these patients before hospital discharging, thus avoiding contagion among their family members or a second coronavirus wave once the lockdown is over.

CONFLICT OF INTERESTS

None.

REFERENCES

Azzi, L., Carcano, G., Gianfagna, F., Grossi, P., Gasperina, D. D., Genoni, A., … Baj, A. (2020). Saliva is a reliable tool to detect SARS-CoV-2. Journal of Infection, 9, 57. https://doi.org/10.1016/j.jinf.2020.04.005
Google Scholar
Braz-Silva, P. H., Pallos, D., Giannecchini, S., & To, K. K. (2020). SARS-CoV-2: What can saliva tell us? Oral Diseases. https://doi.org/10.1111/odi.13365
10.1111/odi.13365
PubMed Web of Science® Google Scholar
Chen, C., Gao, G., Xu, Y., Pu, L., Wang, Q. I., Wang, L., … Zhang, F. (2020). SARS-CoV-2-positive sputum and feces after conversion of pharyngeal samples in patients with COVID-19. Annals of Internal Medicine. https://doi.org/10.7326/M20-0991
10.7326/M20-0991
Web of Science® Google Scholar
Khurshid, Z., Asiri, F. Y. I., & Al Wadaani, H. (2020). Human saliva: Non-invasive fluid for detecting novel Coronavirus (2019-nCoV). International Journal of Environmental Research and Public Health, 17(7), 2225. https://doi.org/10.3390/ijerph17072225
10.3390/ijerph17072225
CAS Web of Science® Google Scholar
Li, D., Wang, D., Dong, J., Wang, N., Huang, H., Xu, H., & Xiac, C. (2020). False-negative results of real-time reverse-transcriptase polymerase chain reaction for severe acute respiratory Syndrome Coronavirus 2: Role of deep-learning-based CT diagnosis and insights from two cases. Korean Journal of Radiology, 21, 505–508. https://doi.org/10.3348/kjr.2020.0146
10.3348/kjr.2020.0146
PubMed Web of Science® Google Scholar
To, K.-W., Tsang, O.-Y., Leung, W.-S., Tam, A. R., Wu, T.-C., Lung, D. C., … Yuen, K.-Y. (2020). Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: An observational cohort study. Lancet Infectious Diseases, 20, 565–574. https://doi.org/10.1016/S1473-3099(20)30196-1
10.1016/S1473-3099(20)30196-1
CAS PubMed Web of Science® Google Scholar
To, K.-W., Tsang, O.-Y., Yip, C.-Y., Chan, K.-H., Wu, T.-C., Chan, J.-C., … Yuen, K.-Y. (2020). Consistent detection of 2019 novel coronavirus in saliva. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa149
10.1093/cid/ciaa149
Web of Science® Google Scholar

Citing Literature

Volume27, IssueS3

Special Issue: COVID‐19, Part 1 of a 2‐Part Series

April 2021

Pages 707-709

Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: A rising concern

Abstract

CONFLICT OF INTERESTS

REFERENCES

Citing Literature

References

Information

About Wiley Online Library

Help & Support

Opportunities

Connect with Wiley

Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: A rising concern

Abstract

CONFLICT OF INTERESTS

REFERENCES

Citing Literature

References

Related

Information