Volume 37, Issue 2 pp. 278-286
ORIGINAL ARTICLE

The Association of Social Determinants of Health With COVID-19 Mortality in Rural and Urban Counties

Rajib Paul PhD

Corresponding Author

Rajib Paul PhD

Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA

Correspondence

Rajib Paul, PhD, Department of Public Health Sciences, University of North Carolina at Charlotte, 9201 University City Blvd., Charlotte, NC 28223, USA.

Email: [email protected]

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Ahmed Arif MBBS, PhD

Ahmed Arif MBBS, PhD

Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA

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Kamana Pokhrel MS

Kamana Pokhrel MS

Health Analytics and Informatics, University of North Carolina at Charlotte, Charlotte, North Carolina, USA

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Subhanwita Ghosh MS

Subhanwita Ghosh MS

Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA

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First published: 22 February 2021
Citations: 49

Funding: Rajib Paul's work was partially supported by the National Foundation, Division of Civil, Mechanical and Manufacturing Innovation (CMMI) award # 1537379.

Abstract

Purpose

To identify the county-level effects of social determinants of health (SDoH) on COVID-19 (corona virus disease 2019) mortality rates by rural–urban residence and estimate county-level exceedance probabilities for detecting clusters.

Methods

The county-level data on COVID-19 death counts as of October 23, 2020, were obtained from the Johns Hopkins University. SDoH data were collected from the County Health Ranking and Roadmaps, the US Department of Agriculture, and the Bureau of Labor Statistics. Semiparametric negative binomial regressions with expected counts based on standardized mortality rates as offset variables were fitted using integrated Laplace approximation. Bayesian significance was assessed by 95% credible intervals (CrI) of risk ratios (RR). County-level mortality hotspots were identified by exceedance probabilities.

Findings

The COVID-19 mortality rates per 100,000 were 65.43 for the urban and 50.78 for the rural counties. Percent of Blacks, HIV, and diabetes rates were significantly associated with higher mortality in rural and urban counties, whereas the unemployment rate (adjusted RR = 1.479, CrI = 1.171, 1.867) and residential segregation (adjusted RR = 1.034, CrI = 1.019, 1.050) were associated with increased mortality in urban counties. Counties with a higher percentage of college or associate degrees had lower COVID-19 mortality rates.

Conclusions

SDoH plays an important role in explaining differential COVID-19 mortality rates and should be considered for resource allocations and policy decisions on operational needs for businesses and schools at county levels.

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