Development pathway

One of the biggest hurdles in ophthalmology, particularly glaucoma, in recent years has been the successful translation of laboratory advances to the clinic. This is not unique to glaucoma – such a problem has been well-described in different spheres of medicine. In fact, a search in PubMed on this subject reveals over 1000 references. A major identifiable bottleneck is the developmental pathway and the adherence to regulatory requirements. Regulatory issues and common problems will be provided, using examples that are well-documented in the field of glaucoma.