ABS15-0054
Free Access
The epithelial-stromal TGFBI corneal dystrophies
First published: 23 September 2015
Summary
Purpose
To correct the IC3D classification system from 2008.
Methods
To examine the corneal specimens of 54 patients with lattice, granular 1 and 2, Reis-Bücklers, and Thiel-Behnke who underwent unilateral penetrating keratoplasty.
Results
All specimens showed epithelial and stromal pathological deposits by staining with HE and Congo red, and distinct alterations of Bowman's layer.
Discussion
The 5 TGFBI dystrophies are to classify from the clinical, genetic, but also from the histopathological aspect as “Epithelial-stromal TGFBI corneal dystrophies.”
