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Water-Soluble Constituents of Cudrania tricuspidata (Carr.) Bur.

Zong-Ping Zheng

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica , Shanghai 201203, China

Department of Natural Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China

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Jing-Yu Liang,

Jing-Yu Liang

Department of Natural Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China

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Li-Hong Hu,

Corresponding Author

Li-Hong Hu

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica , Shanghai 201203, China

*Author for correspondence. Tel (Fax): +86 (0)21 5027 2221; E-mail: <[email protected]>.Search for more papers by this author

Zong-Ping Zheng,

Zong-Ping Zheng

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica , Shanghai 201203, China

Department of Natural Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China

Search for more papers by this author

Jing-Yu Liang,

Jing-Yu Liang

Department of Natural Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China

Search for more papers by this author

Li-Hong Hu,

Corresponding Author

Li-Hong Hu

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica , Shanghai 201203, China

*Author for correspondence. Tel (Fax): +86 (0)21 5027 2221; E-mail: <[email protected]>.Search for more papers by this author

First published: 02 August 2006

https://doi.org/10.1111/j.1744-7909.2006.00227.x

Citations: 28

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Abstract

In order to find new structural and biologically active compounds, the constituents of the bark of Cudrania tricuspidata (Carr.) Bur. were investigated and a new 6-p-hydroxybenzyltaxifolin glucoside, named tricusposide (compound 1), together with 16 known compounds, was isolated by solvent partition, macroporous adsorption resin AB-8, silica gel, Sephadex LH-20 chromatography. Using spectroscopic methods, the structures of the compounds were elucidated as 6-p-hydroxybenzyl taxifolin-7-O-β-D-glucoside (compound 1), dihydroquerctin-7-O-β-D-glucoside (compound 2), dihydrokaempferol-3-O-β-D-glucoside (compound 3), dihydroquercetin (compound 4), peonoside (compound 5), sphaerobioside (compound 6), quercimeritrin (compound 7), genistein (compound 8), aromadendrin (compound 9), kaempferol (compound 10), genistin (compound 11), 3,4-dihydroxystyryl alcohol (compound 12), sucrose (compound 13), 1,3,5,6-tetrahydroxyxanthone (compound 14), gericudranin E (compound 15), gericudranin C (compound 16), and orobol (compound 17). Compounds 2–6, 8, 9, 12–14, and 17 were isolated from this genus for the first time.

(Managing editor: Wei Wang)

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Volume48, Issue8

August 2006

Pages 996-1000

Water-Soluble Constituents of Cudrania tricuspidata (Carr.) Bur.

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Water-Soluble Constituents of Cudrania tricuspidata (Carr.) Bur.

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