Volume 96, Issue 12 pp. 1738-1742

Growth and neurodevelopment outcome of very low birth weight infants delivered by preeclamptic mothers

Rita C Silveira,

Rita C Silveira

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Renato S Procianoy,

Renato S Procianoy

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Maike S Koch,

Maike S Koch

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Ana Cláudia W Benjamin,

Ana Cláudia W Benjamin

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Carolina F Schlindwein,

Carolina F Schlindwein

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Rita C Silveira,

Rita C Silveira

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Renato S Procianoy,

Renato S Procianoy

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Maike S Koch,

Maike S Koch

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Ana Cláudia W Benjamin,

Ana Cláudia W Benjamin

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

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Carolina F Schlindwein,

Carolina F Schlindwein

Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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First published: 12 November 2007

https://doi.org/10.1111/j.1651-2227.2007.00552.x

Citations: 39

Correspondence
Renato S. Procianoy, Rua Tobias da Silva 99 conj 302, Porto Alegre, RS 90570-020, Brazil. Tel: +55-51-33315726 | Fax: +55-51-33312738 | Email: [email protected]

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Abstract

Aim: To investigate growth and neurodevelopment outcome of very low birth weight (VLBW) infants delivered by preeclamptic mothers.

Methods: A cohort including all VLBW infants delivered between December 2003 and May 2005 was followed up to 12 and 18 months corrected age (CA). Exclusion criteria: death before 1 year corrected age, major malformations, deafness and blindness. Weight, length and head circumference were plotted on NCHS curves. Bayley Scales were performed at 12 and 18 months CA.

Results: 40 infants in preeclamptic and 46 in control groups were studied. Birth weight and gestational age were 1148 g ± 236 and 1195 g ± 240, and 31.3 weeks ± 1 and 30.6 weeks ± 2 for preeclamptic and control groups, respectively. At 12 and 18 months, CA, weight for age (Z score) was significantly higher in control than in preeclamptic. PDI scores were higher in preeclamptic than in controls at 18 months CA.

Conclusions: Catch-up of body weight did not occur in the first 18 months CA in preeclamptic infants. Neurodevelopment outcome was better in infants delivered by preeclamptic mothers than in controls at 18 months CA.

References

1 Basso O, Rasmussen S, Weinberg CR, Wilcox AJ, Irgens LM, Skjaerven R. Trends in fetal and infant survival following preeclampsia. JAMA 2006; 296: 1357–62.
10.1001/jama.296.11.1357
CAS PubMed Web of Science® Google Scholar
2 Villar J, Carroli G, Wojdyla D, Abalos E, Giordano D, Ba'aqeel H, et al. for the World Health Organization Antenatal Care Trial Research Group. Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? Am J Obstet Gynecol 2006; 194: 921–31.
10.1016/j.ajog.2005.10.813
PubMed Web of Science® Google Scholar
3 Ngoc NT, Merialdi M, Abdel-Aleem H, Carroli G, Purwar M, Zavaleta N, et al. Causes of stillbirths and early neonatal deaths: data from 7993 pregnancies in six developing countries. Bull World Health Organ 2006; 84: 699–705.
10.2471/BLT.05.027300
PubMed Web of Science® Google Scholar
4 Evans N, Hutchinson J, Simpson JM, Donoghue D, Darlow B, Smart-Henderson D. Prenatal predictors of mortality in very preterm infants cared for the Australian and New Zealand Neonatal Network. Arch Dis Child Fetal Neonatal Ed 2007; 92: F34–40.
10.1136/adc.2006.094169
CAS PubMed Web of Science® Google Scholar
5 Gray PH, O'Callaghan MJO, Mohay HA, Burns YR, King JF. Maternal hypertension and neurodevelopmental outcome in very preterm infants. Arch Dis Child Fetal Neonatal Ed 1998; 79: F88–93.
10.1136/fn.79.2.F88
CAS PubMed Web of Science® Google Scholar
6 Sibai B, Dekker G, Kupfermine M. Pre-eclampsia. Lancet 2005; 365: 785–99.
10.1016/S0140-6736(05)17987-2
PubMed Web of Science® Google Scholar
7 Cheng S-W, Chou H-C, Tsou K-I, Fang L-J, Tsao P-N. Delivery before 32 weeks of gestation form maternal pre-eclampsia: neonatal outcome and 2-year developmental outcome. Early Hum Dev 2004; 76: 39–46.
10.1016/j.earlhumdev.2003.10.004
PubMed Web of Science® Google Scholar
8 Shah DM, Shenai JP, Vaugh WK. Neonatal outcome of premature infants of mother with pre-eclampsia. J Perinatol 1995; 15: 264–7.
CAS PubMed Google Scholar
9 Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000; 183: s1–22.
10.1067/mob.2000.107928
CAS PubMed Web of Science® Google Scholar
10 Ballard JL, Khouri JC, Wedig K, Wang L, Ellers-Walsman L, Lipp R. New ballard score, expanded to include extremely premature infants. J Pediatr 1991; 119: 417–23.
10.1016/S0022-3476(05)82056-6
CAS PubMed Web of Science® Google Scholar
11 Silveira RC, Procianoy RS. Evaluation of interleukin-6, tumor necrosis factor-α and interleukin-1β for early diagnosis of neonatal sepsis. Acta Paediatr 1999; 88: 647–50.
10.1111/j.1651-2227.1999.tb00015.x
CAS PubMed Web of Science® Google Scholar
12 Alexander GR, Himes JH, Kaufman RB, Mor J, Kogan M. A United States national reference for fetal growth. Obstet Gynecol 1996; 87: 163–8.
10.1016/0029-7844(95)00386-X
CAS PubMed Web of Science® Google Scholar
13 Richardson DK, Corcoran JD, Escobar GJ, Lee SK. SNAP-II and SNAPPE-II: Simplified newborn illness severity and mortality risk scores. J Pediatr 2001; 138: 92–100.
10.1067/mpd.2001.109608
CAS PubMed Web of Science® Google Scholar
14 Vohr B, Wright LL, Dusick AM, Mele L, Verter J, Steichen JJ, et al. Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993–1994. Pediatrics 2000; 105: 1216–26.
10.1542/peds.105.6.1216
CAS PubMed Web of Science® Google Scholar
15 Knops NBB, Sneeuw KCA, Brand R, Hille ETM, Ouden L, Wit J-M, et al. Catch-up growth up to ten years of age in children born very preterm or with very low birth weight. BMC Pediatr 2005; 5: 26. http://www.biomedcentral.com/1471-2431/5/26 [Accessed 12 July 2006.
10.1186/1471-2431-5-26
PubMed Google Scholar
16 Sung I-K, Vohr B, Oh W. Growth and neurodevelopmental outcome of very low birth weight infants with intrauterine growth retardation: comparison with control subjects matched by birth weight and gestational age. J Pediatr 1993; 123: 618–24.
10.1016/S0022-3476(05)80965-5
PubMed Web of Science® Google Scholar
17 Strauss RS, Dietz WH. Effects of intrauterine growth retardation in premature infants on early childhood growth. J Pediatr 1997; 130: 95–102.
10.1016/S0022-3476(97)70316-0
CAS PubMed Web of Science® Google Scholar
18 Gutbrod T, Wolke D, Soehne B, Ohrt B, Riegel K. Effects of gestation and birth weight on the growth and developmental of very low birth weight small for gestational age infants: a matched group comparison. Arch Dis Child Fetal Neonatal Ed 2000; 82: F208–14.
10.1136/fn.82.3.F208
CAS PubMed Web of Science® Google Scholar
19 Hack M, Breslau N, Fanaroff AA. Differential effects of intrauterine and postnatal growth failure in infants of very low birth weight. Am J Dis Child 1989; 143: 63–8.
CAS PubMed Web of Science® Google Scholar
20 Hajnal-Latal B, Von Siebenthal K, Kovari H, Bucher HU, Largo RH. Postnatal growth in VLBW infants: significant association with neurodevelopmental outcome. J Pediatr 2003; 143: 163–70.
10.1067/S0022-3476(03)00243-9
PubMed Web of Science® Google Scholar
21 Ehrenkranz RA, Dusick AM, Vohr B, Wright LL, Wrage L, Poole WK, et al. Growth in the Neonatal Intensive Care Unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants. Pediatrics 2006; 117: 1253–61.
10.1542/peds.2005-1368
PubMed Web of Science® Google Scholar
22 Gortner L, Van Husen M, Thyen U, Gembruch U, Friedrich H-J, Landmann E. Outcome in preterm small for gestational age infants compared to appropriated for gestational age preterms at the age of 2 years: a prospective study. Eur J Obstet Gynecol Reprod Biol 2003; 110: S93–7.
10.1016/S0301-2115(03)00178-7
PubMed Web of Science® Google Scholar
23 Vermeulen GM, Bruinse HW, De Vries LS. Perinatal risk factors for adverse neurodevelopmental outcome after spontaneous preterm birth. Eur J Obstet Gynecol Reprod Biol 2001; 99: 207–12.
10.1016/S0301-2115(01)00383-9
CAS PubMed Web of Science® Google Scholar
24 American Academy of Pediatrics. Follow-up Care of high-risk infants. Pediatrics 2004; 114: 1377–97.
10.1542/peds.2004-0866
Web of Science® Google Scholar
25 Spinillo A, Iasci A, Capuzo E, Egbe TO, Colona L, Fazzi E. Two-year neurodevelopmental outcome after expectant management and indicated preterm delivery in hypertensive pregnancies. Acta Obstet Gynecol Scand 1994; 73: 625–9.
10.3109/00016349409013455
PubMed Web of Science® Google Scholar
26 Hack M, Weissman B, Borawski-Clark E. Catch-up growth during childhood among very low-birth-weight children. Arch Pediatr Adolesc Med 1996; 150: 1122–9.
10.1001/archpedi.1996.02170360012002
CAS PubMed Web of Science® Google Scholar
27 Van Beek E, Peeters LL. Pathogenesis of preeclampsia: a comprehensive model. Obstet Gynecol Surv 1998; 53: 233–9.
10.1097/00006254-199804000-00021
PubMed Google Scholar
28 Xiong X, Demianczuk NN, Saunders D, Wang F-L, Fraser WD. Impact of Preeclampsia and gestational hypertension on birth weight by gestational age. Am J Epidemiol 2002; 155: 203–9.
10.1093/aje/155.3.203
PubMed Web of Science® Google Scholar

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Volume96, Issue12

December 2007

Pages 1738-1742

Growth and neurodevelopment outcome of very low birth weight infants delivered by preeclamptic mothers

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Growth and neurodevelopment outcome of very low birth weight infants delivered by preeclamptic mothers

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