Key Cellular Components and Interactive Histocompatibility Molecules Regulating Tolerance to the Fetal Allograft
Patrick S. Spencer
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorSoukaina M. Hakam
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorPhillipe P. Laissue
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorAsma Jabeen
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorPallavi Jain
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorSoren Hayrabedyan
Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, Sophia, Bulgaria
Search for more papers by this authorKrassimira Todorova
Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, Sophia, Bulgaria
Search for more papers by this authorAlyssa Blanch
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorJames M.W.R. McElhinney
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorNiwedhie Muhandiram
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorShaza Alkhatib
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorGill B. Dealtry
Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, South Africa
Search for more papers by this authorJose M. Miranda-Sayago
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorCorresponding Author
Nelson Fernández
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Correspondence
Nelson Fernández, School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester C04 3SQ, UK.
E-mail: [email protected]
Search for more papers by this authorPatrick S. Spencer
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorSoukaina M. Hakam
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorPhillipe P. Laissue
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorAsma Jabeen
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorPallavi Jain
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorSoren Hayrabedyan
Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, Sophia, Bulgaria
Search for more papers by this authorKrassimira Todorova
Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, Sophia, Bulgaria
Search for more papers by this authorAlyssa Blanch
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorJames M.W.R. McElhinney
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorNiwedhie Muhandiram
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorShaza Alkhatib
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorGill B. Dealtry
Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, South Africa
Search for more papers by this authorJose M. Miranda-Sayago
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Search for more papers by this authorCorresponding Author
Nelson Fernández
School of Biological Sciences, University of Essex, Colchester, Essex, UK
Correspondence
Nelson Fernández, School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester C04 3SQ, UK.
E-mail: [email protected]
Search for more papers by this authorAbstract
Implantation is a major landmark in life. It involves the correct apposition of the embryo in the maternal endometrium. The cellular environment influences placenta development, and direct contact of the fetus with maternal tissues is achieved through decidual cells. At the decidua, and at systemic level, the correct balance of cells potentially acting as antigen-presenting cells and histocompatibility products play a pivotal role in achieving feto–maternal tolerance. Here, we review some of the current issues associated with the interplay between cells and molecules needed for pregnancy development.
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