Testicular choriocarcinoma metastatic to skin and multiple organs. Two case reports and review of literature

Corresponding Author

Xinhua Chen

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

Frank Reidy Research Center, Norfolk, VA, USA

Xinhua Chen, The 1st Affiliated Hospital of Medical
School, Zhejiang University, Hangzhou, Zhejiang, China
Tel:+86-571-87236570
Fax:+86-571-87236466
e-mail: [email protected]Search for more papers by this author

Linjie Xu,

Linjie Xu

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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Xinmei Chen,

Xinmei Chen

Shandong University of Traditional Chinese Medicine, Jinan Shandong, China

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Xiaodong Teng,

Xiaodong Teng

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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Shusen Zheng,

Shusen Zheng

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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Xinhua Chen,

Corresponding Author

Xinhua Chen

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

Frank Reidy Research Center, Norfolk, VA, USA

Linjie Xu,

Linjie Xu

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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Xinmei Chen,

Xinmei Chen

Shandong University of Traditional Chinese Medicine, Jinan Shandong, China

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Xiaodong Teng,

Xiaodong Teng

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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Shusen Zheng,

Shusen Zheng

The 1st Affiliated Hospital of Medical School, Zhejiang University, Hangzhou, Zhejiang, China

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First published: 11 February 2010

https://doi.org/10.1111/j.1600-0560.2009.01296.x

Citations: 14

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Abstract

Two cases of males with subcutaneous masses as the first clinical sign of testicular choriocarcinoma are reported. The urine and serum human chorionic gonadotropin (hCG) test confirmed high level hCG from male choriocarcinoma. These cases, although very rare, can be a great diagnostic and therapeutic challenge and should be considered in the differential diagnosis of subcutaneous masses occurring in young males.

Chen X, Xu L, Chen X, Teng X, Zheng S. Testicular choriocarcinoma metastatic to skin and multiple organs. Two case reports and review of literature.

References

1 Mountzios G, Pavlakis G, Terpos E, et al. Concurrent development of testicular seminoma and choriocarcinoma of the superior mediastinum, presented as cervical mass: a case report and implications about pathogenesis of germ-cell tumours. BMC Clin Pathol 2006; 6: 8.
10.1186/1472-6890-6-8
PubMed Google Scholar
2 Spencer PS, Helm TN. Skin metastases in cancer patients. Cutis 1987; 39(2): 119.
CAS PubMed Web of Science® Google Scholar
3 Brownstein MH, Helwig EB. Metastatic tumors of the skin. Cancer 1972; 29(5): 1298.
10.1002/1097-0142(197205)29:5<1298::AID-CNCR2820290526>3.0.CO;2-6
CAS PubMed Web of Science® Google Scholar
4 Saito J, Miyagawa Y, Kamoto A, et al. Testicular cancer metastatic to multiple organs including the stomach, kidneys, and skin: a case report. Hinyokika Koyo 2006; 52(4): 297.
PubMed Google Scholar
5 Burd L, Roberts D, Olson M, Odendaal H. Ethanol and the placenta: a review. J Matern Fetal Neonatal Med 2007; 20(5): 361.
10.1080/14767050701298365
CAS PubMed Web of Science® Google Scholar
6 Sofikerim M, Dogan I, Ekici S, Bayraktar N, Ozen H. Testicular choriocarcinoma metastatic to the skin. Int Urol Nephrol 2005; 37(4): 759.
10.1007/s11255-005-1664-4
PubMed Google Scholar
7 Tinkle LL, Graham BS, Spillane TJ, Barr RJ. Testicular choriocarcinoma metastatic to the skin: an additional case and literature review. Cutis 2001; 67(2): 117.
CAS PubMed Web of Science® Google Scholar
8 Kiriyama T, Yoshida O. A review of the cases of testicular tumors reported in the annual of pathological autopsy cases in Japan. Hinyokika Kiyo 1983; 29(2): 155.
CAS PubMed Google Scholar
9 Bredael JJ, Vugrin D, Whitmore WF, Jr. Autopsy findings in 154 patients with germ cell tumors of the testis. Cancer 1982; 50(3): 548.
10.1002/1097-0142(19820801)50:3<548::AID-CNCR2820500327>3.0.CO;2-2
CAS PubMed Web of Science® Google Scholar
10 Figurin KM. Effect of retroperitoneal lymphadenectomy on late therapeutic results in testicular tumors. Vopr Onkol 1981; 27(4): 70.
CAS PubMed Web of Science® Google Scholar
11 Wettlaufer JN. Stage III germinal testis tumors: aggressive approach. J Urol 1976; 116(5): 593.
10.1016/S0022-5347(17)58924-7
CAS PubMed Web of Science® Google Scholar
12 Luna MA, Valenzuela-Tamariz J. Germ-cell tumors of the mediastinum, postmortem findings. Am J Clin Pathol 1976; 65(4): 450.
10.1093/ajcp/65.4.450
CAS PubMed Web of Science® Google Scholar
13 Chhieng DC, Jennings TA, Slominski A, Mihm MC, Jr. Choriocarcinoma presenting as a cutaneous metastasis. J Cutan Pathol 1995; 22(4): 374.
10.1111/j.1600-0560.1995.tb01423.x
CAS PubMed Web of Science® Google Scholar
14 Brownstein MH, Helwig EB. Patterns of cutaneous metastasis. Arch Dermatol 1972; 105(6): 862.
10.1001/archderm.1972.01620090034008
CAS PubMed Web of Science® Google Scholar
15 Tharakaram S. Metastases to the skin. Int J Dermatol 1988; 27(4): 240.
10.1111/j.1365-4362.1988.tb03216.x
CAS PubMed Web of Science® Google Scholar
16 Rim JH, Moon SE, Chang MS, Kim JA. Metastatic hepatocellular carcinoma of gingiva mimicking pyogenic granuloma. J Am Acad Dermatol 2003; 49(2): 342.
10.1067/S0190-9622(03)00416-X
PubMed Web of Science® Google Scholar
17 Shimizu S, Nagata Y, Han-yaku H. Metastatic testicular choriocarcinoma of the skin. Report and review of the literature. Am J Dermatopathol 1996; 18(6): 633.
10.1097/00000372-199612000-00016
CAS PubMed Web of Science® Google Scholar
18 Stenman UH, Alfthan H, Hotakainen K. Human chorionic gonadotropin in cancer. Clin Biochem 2004; 37(7): 549.
10.1016/j.clinbiochem.2004.05.008
CAS PubMed Web of Science® Google Scholar

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Volume37, Issue4

April 2010

Pages 486-490

Testicular choriocarcinoma metastatic to skin and multiple organs. Two case reports and review of literature

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Testicular choriocarcinoma metastatic to skin and multiple organs. Two case reports and review of literature

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