Volume 12, Issue 6 pp. 520-527
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Neurotropic melanoma of the face invading the maxillary nerve

T. F. C. S. Warner

Corresponding Author

T. F. C. S. Warner

The Departments of Surgical Pathology, University of Wisconsin Hospital, Madison, Wisconsin, U.S.A.

Thomas F. Wanter, M. D., University of Wisconsin Hospital and Clinics, Department of Surgical Pathology, 600 Highland Avenue. Room E5/3 17, Madison, W1 53791, USA.Search for more papers by this author
C. N. Ford

C. N. Ford

The Departments of Otorhinolaryngology, University of Wisconsin Hospital, Madison, Wisconsin, U.S.A.

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G. R. Hafuz

G. R. Hafuz

The Departments of Surgical Pathology, University of Wisconsin Hospital, Madison, Wisconsin, U.S.A.

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First published: December 1985
Citations: 16

Abstract

Neurotropic melanoma is a variant of desmoplastic melanoma which, in addition to a spindle-cell vertical component and fibrosis, exhibits a lascicular growth pattern and invades cutaneous nerves. Here we describe a neurotropic melanoma which arose in a small Ientigo maligna melanoma and invaded the maxillary nerve for a distance of 5 cm. Ultrastructural features were similar to those of previously described neurotropic melanomas and tumor fascicles contained S-100 protein and neuron-specific enolase immunoreactivity.

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