Vasomotor Reactivity Is Similarly Impaired in Patients with Alzheimer's Disease and Patients with Amyloid Hemorrhage

Manuel Menendez-Gonzalez MD

From the Neurology Department, Hospital Álvarez-Buylla, Mieres, Spain (MMG, RR); Neurology Department, Hospital Universitario de Albacete, Albacete, Spain (JGG); Neurology Department, Hospital Universitario Central de Asturias, Oviedo, Spain (SC); and Neurology Department, Hospital de Tenerife, Tenerife, Spain (JR).

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Jorge Garcia-Garcia MD,

Jorge Garcia-Garcia MD

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Sergio Calleja MD,

Sergio Calleja MD

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Jose Rojo MD,

Jose Rojo MD

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Renee Ribacoba MD,

Renee Ribacoba MD

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Manuel Menendez-Gonzalez MD,

Manuel Menendez-Gonzalez MD

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Jorge Garcia-Garcia MD,

Jorge Garcia-Garcia MD

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Sergio Calleja MD,

Sergio Calleja MD

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Jose Rojo MD,

Jose Rojo MD

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Renee Ribacoba MD,

Renee Ribacoba MD

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First published: 24 March 2011

https://doi.org/10.1111/j.1552-6569.2009.00438.x

Citations: 14

Correspondence: Address correspondence to Manuel Menéndez González, MD, Hospital Álvarez-Buylla, Unidad de Neurología, Murias s/n, 33616, Mieres, Spain. E-mail: [email protected].

J Neuroimaging 2011;21:e83-e85.

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Abstract

ABSTRACT

Cerebral amyloid angiopathy (CAA) might alter cerebral hemodynamics. Impairment of vasomotor reactivity may constitute a biomarker of amyloid angiopathy and therefore it may be useful to distinguish disorders with CAA from other conditions. The aim of this study was to assess the vasomotor reactivity in two conditions characterized by CAA: Alzheimer's disease and amyloid hemorrhage.

METHODS

We assessed the vasomotor using transcranial Doppler and the breath-holding method.

RESULTS

Responses obtained in controls were higher than in patients with Alzheimer's or with antecedent of amyloid hemorrhage while there was no statistical difference in the comparison between these last two groups.

CONCLUSION

The vasomotor reactivity seems to be similarly impaired in Alzheimer's disease and amyloid hemorrhage patients.

References

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Volume21, Issue2

April 2011

Pages e83-e85

Vasomotor Reactivity Is Similarly Impaired in Patients with Alzheimer's Disease and Patients with Amyloid Hemorrhage

Abstract

ABSTRACT

METHODS

RESULTS

CONCLUSION

References

Citing Literature

References

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Vasomotor Reactivity Is Similarly Impaired in Patients with Alzheimer's Disease and Patients with Amyloid Hemorrhage

Abstract

ABSTRACT

METHODS

RESULTS

CONCLUSION

References

Citing Literature

References

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