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Characterization of an α-Tubulin Gene of Cryptosporidium parvum
MARÍA-TERESA BONAFONTE,
DEANNA GARMON, JAN R. MEAD,
MARÍA-TERESA BONAFONTE
VA Medical Center, Decatur, Georgia 30033
Search for more papers by this authorCorresponding Author
JAN R. MEAD
VA Medical Center and Emory University, 1670 Clairmont Rd, Decatur, Georgia, 30033, USA
Corresponding Author: Dr. J. Mead—Telephone number: 404-321-6111 ×2545; FAX number: 404-728-7726; Email: [email protected]Search for more papers by this authorMARÍA-TERESA BONAFONTE,
DEANNA GARMON, JAN R. MEAD,
MARÍA-TERESA BONAFONTE
VA Medical Center, Decatur, Georgia 30033
Search for more papers by this authorCorresponding Author
JAN R. MEAD
VA Medical Center and Emory University, 1670 Clairmont Rd, Decatur, Georgia, 30033, USA
Corresponding Author: Dr. J. Mead—Telephone number: 404-321-6111 ×2545; FAX number: 404-728-7726; Email: [email protected]Search for more papers by this authorABSTRACT
A gene encoding an α-tubulin of Cryptosporidium parvum was isolated and characterized. It had no introns, and encoded a 441-amino acid protein whose predicted ORF represented a typical α-tubulin protein with a MW of 50.5 kDa. This tubulin had an amino acid sequence similarity with Apicomplexa Plasmodium falciparum and Toxoplasma gondii higher than 88% and shared a number of conserved motifs.
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