Volume 50, Issue 11 pp. 2487-2496

Migralepsy: A call for a revision of the definition

Grazia Sances

Grazia Sances

Headache Unit, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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Elena Guaschino

Elena Guaschino

Headache Unit, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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Piero Perucca

Piero Perucca

Unit of Sleep Medicine and Epilepsy, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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Marta Allena

Marta Allena

Headache Unit, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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Natascia Ghiotto

Natascia Ghiotto

Neurosonology Service, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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Raffaele Manni

Raffaele Manni

Unit of Sleep Medicine and Epilepsy, IRCCS “C. Mondino Institute of Neurology” Foundation, Pavia, Italy

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First published: 23 October 2009
Citations: 63
Address correspondence to Dr Grazia Sances, Headache Unit, IRCCS “C. Mondino Institute of Neurology” Foundation, Via Mondino 2, 27100 Pavia, Italy. E-mail: [email protected]

Summary

Migralepsy is an ill-defined nosologic entity, with only a few cases described in the literature. In the 2004 International Classification for Headache Disorders (ICHD-II), the International Headache Society proposed that the following diagnostic criteria should be met: (1) migraine fulfilling criteria for 1.2 Migraine with aura (MA) and (2) a seizure fulfilling diagnostic criteria for one type of epileptic attack occurs during or within 1 h after a migraine aura. Herein, by presenting a case with symptoms suggestive of migralepsy and by reviewing all previous cases described in the literature, we discuss the challenges of differentiating this condition from epileptic seizures, as well as the inaccuracy of the current ICHD-II definition.

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