Periictal Diffusion-Weighted Imaging in a Case of Lesional Epilepsy

Corresponding Author

B. Diehl

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

Address correspondence and reprint requests to Dr. B. Diehl at 9500 Euclid Avenue, Box 655 Cleveland, OH 44195, U.S.A. [email protected]Search for more papers by this author

I. Najm,

I. Najm

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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P. Ruggieri,

P. Ruggieri

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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N. Foldvary,

N. Foldvary

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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A. Mohamed,

A. Mohamed

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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J. Tkach,

J. Tkach

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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H. Morris,

H. Morris

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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G. Barnett,

G. Barnett

Neurosurgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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E. Fisher,

E. Fisher

Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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J. Duda,

J. Duda

Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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H. O. Lüders,

H. O. Lüders

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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B. Diehl,

Corresponding Author

B. Diehl

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

Address correspondence and reprint requests to Dr. B. Diehl at 9500 Euclid Avenue, Box 655 Cleveland, OH 44195, U.S.A. [email protected]Search for more papers by this author

I. Najm,

I. Najm

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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P. Ruggieri,

P. Ruggieri

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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N. Foldvary,

N. Foldvary

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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A. Mohamed,

A. Mohamed

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

Search for more papers by this author

J. Tkach,

J. Tkach

Radiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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H. Morris,

H. Morris

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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G. Barnett,

G. Barnett

Neurosurgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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E. Fisher,

E. Fisher

Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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J. Duda,

J. Duda

Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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H. O. Lüders,

H. O. Lüders

Departments of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, U.S.A.

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First published: 02 August 2005

https://doi.org/10.1111/j.1528-1157.1999.tb02056.x

Citations: 54

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Abstract

Summary: Purpose: Diffusion-weighted MR imaging (DWI) has been used for the early diagnosis of acute ischemic lesions in humans and in animal models of focal status epilepticus. We hypothesized that DWI may be a sensitive, noninvasive tool for the localization of the epileptogenic area during the periictal period.

Methods: A periictal DWI study was performed on a 35-year-old patient during focal status epilepticus with repetitive prolonged focal motor seizures originating from a lesion in the right frontal lobe. DWI results were analyzed visually and by calculating apparent diffusion coefficient (ADC) maps.

Results: On DWI, a single area of signal increase (decrease in ADC) was found in the region of focal electrocorticographic seizures that was mapped intraoperatively.

Conclusions: Ictal/postictal DWI may be a useful technique for seizure localization in patients with lesional epilepsy.

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Volume40, Issue11

November 1999

Pages 1667-1671

Periictal Diffusion-Weighted Imaging in a Case of Lesional Epilepsy

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Periictal Diffusion-Weighted Imaging in a Case of Lesional Epilepsy

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