Electrical Stimulation of the Contralateral Mesial Temporal Structure Induces an Ipsilateral Seizure Pattern in Mesial Temporal Lobe Epilepsy

Corresponding Author

Yushi Inoue

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

Address correspondence and reprint requests to Dr. Y. Inoue at National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama 886, Shizuoka 420–8688, Japan. [email protected]Search for more papers by this author

Tadahiro Mihara,

Tadahiro Mihara

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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Takayasu Tottori,

Takayasu Tottori

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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Masakazu Seino,

Masakazu Seino

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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Yushi Inoue,

Corresponding Author

Yushi Inoue

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

Tadahiro Mihara,

Tadahiro Mihara

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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Takayasu Tottori,

Takayasu Tottori

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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Masakazu Seino,

Masakazu Seino

National Epilepsy Center, Shizuoka Higashi Hospital, Shizuoka, Japan

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First published: 02 August 2005

https://doi.org/10.1111/j.1528-1157.1999.tb02046.x

Citations: 6

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Abstract

Summary: Purpose: We examined the mode of seizure development induced by electrical stimulation in patients with mesial temporal lobe epilepsy.

Methods: Of 25 patients undergoing intracranial EEG evaluation and electrical stimulation ipsilateral to the presumed site of habitual seizure origin, 17 patients had additional stimulation studies on the contralateral temporal lobe.

Results: Fourteen of the 25 patients had seizures induced with ipsilateral stimulation, and two of the 17 patients had seizures with contralateral stimulation. Seizures induced by ipsilateral stimulation started in the ipsilateral temporal lobe, whereas those induced by contralateral stimulation originated from the ipsilateral temporal lobe structure and were identical to the habitual seizures.

Conclusions: Electrical stimulation of the temporal lobe structure opposite the site of habitual seizure origin is said to induce a seizure rarely. However, according to our preliminary results, if contralateral stimulation elicits a habitual seizure in the ipsilateral temporal lobe, it might be considered additional confirmatory evidence of seizure lateralization.

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Volume40, Issue11

November 1999

Pages 1602-1609

Electrical Stimulation of the Contralateral Mesial Temporal Structure Induces an Ipsilateral Seizure Pattern in Mesial Temporal Lobe Epilepsy

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Electrical Stimulation of the Contralateral Mesial Temporal Structure Induces an Ipsilateral Seizure Pattern in Mesial Temporal Lobe Epilepsy

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