Volume 3, Issue 1 pp. 55-60

Full Access

FLASH AND PATTERN VEPs: EXAMPLES OF CASES OF HYSTERICAL AMBLYOPIA AND PROVOKED VISUAL IMPAIRMENT (UHTHOFF'S SIGN)

F. MacCANA,

F. MacCANA

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

*Fellow of the British College of Ophthalmic Opticians (Optometrists).

Search for more papers by this author

S. K. Bhargava,

S. K. Bhargava

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

Search for more papers by this author

J. J. Kulikowski,

Corresponding Author

J. J. Kulikowski

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

†To whom correspondence should be addressed.Search for more papers by this author

F. MacCANA,

F. MacCANA

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

*Fellow of the British College of Ophthalmic Opticians (Optometrists).

Search for more papers by this author

S. K. Bhargava,

S. K. Bhargava

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

Search for more papers by this author

J. J. Kulikowski,

Corresponding Author

J. J. Kulikowski

Department of Ophthalmic Optics, UMIST, PO Box 88, Manchester M60 1QD, U.K.; and Manchester Royal Eye Hospital, U.K.

†To whom correspondence should be addressed.Search for more papers by this author

First published: January 1983

https://doi.org/10.1111/j.1475-1313.1983.tb00580.x

Citations: 7

About

PDF

Tools

Share a link

Email
Wechat
Bluesky

Abstract

Abstract The diagnostic application of averaged visual evoked potentials (VEPs) is illustrated in the investigation of hysterical amblyopia and multiple sclerosis. Averaged VEPs elicited either by a flash of light or a presentation of a grating lasting 100 ms were recorded from the occiput of patients. All the VEPs in hysterical amblyopia were normal. In multiple sclerosis the flash VEPs looked normal for both eyes, whereas the VEPs elicited by grating (2 and 5 c/deg) showed an increase in the latency of the first positive wave, again for both eyes. After physical exercise the VEPs from the right eye were dramatically reduced in amplitude (Uhthoff s sign).

Reference

Abadi, R. V., Kulikowski, J. J. and Meudell, P. (1981) Visual performance in a case of visual agnosia. In M. Hof and G. Mohn (Eds) Functional Recovery from Brain Damage. Elsevier, Amsterdam .
Google Scholar
Halliday, A. M. (1978) Clinical application of evoked potentials. In Recent Advances in Clinical Neurology, pp. 47–73. Churchill & Livingstone, Edinburgh .
Google Scholar
Halliday, A. M., McDonald, W. I. and Mushin, J. (1973) Visual evoked responses in diagnosis of multiple sclerosis. Br. med. J. 4, 661–664.
10.1136/bmj.4.5893.661
CAS PubMed Web of Science® Google Scholar
Ikeda, H., Tremain, K. E. and Sanders, M. D. (1978) Neurophysiological investigation in optic nerve disease: combined assessment of the visual evoked responses and electroretinogram. Br. J. Ophthal. 62, 227–239.
10.1136/bjo.62.4.227
Google Scholar
Kulikowski, J. J. (1972) Relation of psychophysics and electrophysiology. Trace, Paris 6, 64–69.
Google Scholar
Kulikowski, J. J. (1977a) Visual evoked potentials as a measure of visibility. In J. E. Desmedt (Ed.) Visual Evoked Potentials in Man; New Developments. Clarendon Press, Oxford .
Google Scholar
Kulikowski, J. J. (1977b) Separation of occipital potentials related to the detection of pattern and movement. In J. E. Desmedt (Ed.) Visual Evoked Potentials in Man: New Developments. Clarendon Press, Oxford .
Google Scholar
Kulikowski, J. J. (1978) Pattern and movement detection in man and rabbit: separation and comparison of occipital potentials. Vision Res. 18, 183–189.
10.1016/0042-6989(78)90184-0
CAS PubMed Web of Science® Google Scholar
Kulikowski, J. J. and Leisman, G. (1973) The effect of nitrous oxide on the relation between the evoked potential and contrast threshold. Vision Res. 13, 2079–2086.
10.1016/0042-6989(73)90184-3
CAS PubMed Web of Science® Google Scholar
MacCana, F., Kulikowski, J. J. and Bhargava, S. K. (1983) Changes in spatial resolution for pattern and movement detection in clinical cases. Ophthal. Physiol. Opt. 3, 47–54.
10.1111/j.1475-1313.1983.tb00579.x
CAS PubMed Web of Science® Google Scholar
McAlpine, D., Lumsden, C. E. and Acheson, E. D. (1972) Multiple Sclerosis: A Reappraisal. Livingstone Press, Edinburgh .
Web of Science® Google Scholar
McDonald, W. I. (1974) Pathophysiology in multiple sclerosis. Brain 97, 179–196.
10.1093/brain/97.1.179
CAS PubMed Web of Science® Google Scholar
McDonald, W. I. (1977) Pathophysiology of conduction in central nerve fibres. In J. E. Desmedt (Ed.) Visual Evoked Potentials in Man: New Developments. Clarendon Press, Oxford .
Google Scholar
Persson, H. E. and Sachs, C. (1978) Provoked visual impairment in multiple sclerosis studied by visual evoked responses. Electroenceph. clin. Neurophysiol. 44, 664–668.
10.1016/0013-4694(78)90131-1
CAS PubMed Web of Science® Google Scholar
Rasminsky, M. and Sears, T. A. (1972) Internodal conduction in undissected demyelinated nerve fibres. J. Physiol., Lond. 227, 232–350.
10.1113/jphysiol.1972.sp010035
Google Scholar
Regan, D., Murray, T. J. and Silver, R. (1977) Effect of body temperature on the visual evoked potential delay and visual perception in multiple sclerosis. J. Neurol. Neurosurg. Psychiat. 40, 1083–1091.
10.1136/jnnp.40.11.1083
CAS PubMed Web of Science® Google Scholar
Uhthoff, W. (1889) Untersuchungen über die bie der mutliplen Herdsklerose vorkommenden Augenstorungen. Arch. Psychiat. NervKrankh. 21, 303–420.
Google Scholar

Citing Literature

Volume3, Issue1

January 1983

Pages 55-60

FLASH AND PATTERN VEPs: EXAMPLES OF CASES OF HYSTERICAL AMBLYOPIA AND PROVOKED VISUAL IMPAIRMENT (UHTHOFF'S SIGN)

Abstract

Reference

Citing Literature

References

Information

About Wiley Online Library

Help & Support

Opportunities

Connect with Wiley

FLASH AND PATTERN VEPs: EXAMPLES OF CASES OF HYSTERICAL AMBLYOPIA AND PROVOKED VISUAL IMPAIRMENT (UHTHOFF'S SIGN)

Abstract

Reference

Citing Literature

References

Related

Information