Volume 24, Issue 4 pp. 433-435

Fatal liver injury associated with clopidogrel

Sarrah Kastalli

Sarrah Kastalli

Centre National de Pharmacovigilance, 9 Avenue du Dr. Zouheir Essafi 1006 Tunis, Tunisia

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Sihem El Aïdli

Sihem El Aïdli

Centre National de Pharmacovigilance, 9 Avenue du Dr. Zouheir Essafi 1006 Tunis, Tunisia

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Ahmed Zaïem

Corresponding Author

Ahmed Zaïem

Centre National de Pharmacovigilance, 9 Avenue du Dr. Zouheir Essafi 1006 Tunis, Tunisia

Correspondence and reprints: [email protected]; [email protected]Search for more papers by this author
Hatem Ben Abdallah

Hatem Ben Abdallah

Department of Gastroenterology. Military Hospital, Mont Fluery 1008 Tunis, Tunisia

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Riadh Daghfous

Riadh Daghfous

Centre National de Pharmacovigilance, 9 Avenue du Dr. Zouheir Essafi 1006 Tunis, Tunisia

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First published: 06 July 2010
Citations: 11

Abstract

Clopidogrel, an adenosine diphosphate receptor blocker, is widely used as an adjunctive antiplatelet therapy in acute coronary syndrome and percutaneous coronary stenting. It appears to be a safe drug with few occurrences of liver side-effects that usually resolved after drug withdrawal. We report a serious liver injury with fatal outcome in a 63-year-old man developed 19 days after starting clopidogrel for percutaneous coronary stenting.

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