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The postnatal development of the benzodiazepine receptor in the cerebral cortex and cerebellum of the rat
J. M. Candy,
I. L. Martin,
J. M. Candy
MRC Neuropharmacology Unit, The Medical School, Edgbaston, Birmingham, B15 2TJ., U.K.
Search for more papers by this authorI. L. Martin
MRC Neuropharmacology Unit, The Medical School, Edgbaston, Birmingham, B15 2TJ., U.K.
Search for more papers by this authorJ. M. Candy,
I. L. Martin,
J. M. Candy
MRC Neuropharmacology Unit, The Medical School, Edgbaston, Birmingham, B15 2TJ., U.K.
Search for more papers by this authorI. L. Martin
MRC Neuropharmacology Unit, The Medical School, Edgbaston, Birmingham, B15 2TJ., U.K.
Search for more papers by this author
REFERENCES
- Aghajanian, G. K. & Bloom, F. E. (1967) The formation of synaptic junctions in developing rat brain: a quantitative electron microscopic study. Brain Res. 6, 716–727.
- Altman, J. (1972) Postnatal development of the cerebellar cortex in the rat. II. Phases in the maturation of Purkinje cells and of the molecular layer. J. camp. Neurol. 145, 399–464.
- Braestrup, C. & Squires, R. F. (1977) Specific benzodiazepine receptors in rat brain characterised by high-affinity [3H]diazepam binding. Proc. natn. Acad. Sci. U.S.A. 74, 3805–3809.
- Braestrup, C. & Nielsen, M. (1978) Ontogenetic development of benzodiazepine receptors in the rat brain. Brain Res. 147, 170–173.
- Braestrup, C., Albrechtsen, R. & Squires, R. F. (1977) High densities of henzodiazepine receptors in human cortical areas. Nature, Lond. 269, 702–704.
- Brownlee, K. A. (1965) Statistical Theory and Methodology, 2nd ed. pp. 346–349, John Wiley, New york .
- Coyle, J. T. & Enna, S. J. (1976) Neurochemical aspects of the ontogenesis of Gabanergic neurons in the rat brain. Brain Res. 111, 119–133.
- Coyle, J. T. & Pert, C. B. (1976) Ontogenetic development of [3H]naloxone binding in rat brain. Neuropharmacology 15, 555–560.
- Coyle, J. T. & Yamamura, H. I. (1976) Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain. Brain Res. 118, 429–440.
- Eayrs, J. T. & Goodhead, B. (1959) Postnatal development of the cerebral cortex in the rat. J. Anat. 93, 385–402.
- Geiger, P. J. & Besman, S. P. (1972) Protein determination by Lowry's method in the presence of sulfhydryl reagents. Analyt. Biochem. 49, 467–473.
- Harden, T. K., Wolfe, B. B., Sporn, J. R., Perkins, J. P. & Molinoff, P. B. (1977) Ontogeny of β-adrenergic receptors in rat cerebral cortex. Brain Res. 125, 99–108.
- Mohler, H. & Okada, T. (1977) Properties of [3H]diazepam binding to benzodiazepine receptors in rat cerebral cortex. Life Sci. 20, 2101–2110.
- Snedecor, G. W. & Cohran, W. G. (1967) Statistical Methods, 6th ed., pp. 432–435. Iowa State University Press, Iowa .
- Squires, R. F. & Braestrup, C. (1977) Benzodiazepine receptors in rat brain. Nature, Lond. 266, 732–734.
- Woodward, D. J., Hoffer, B. J., Siggins, G. R. & Bloom, F. E. (1971) The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar Purkinje cells. Brain Res. 34, 73–97.
