Prevalence of patent foramen ovale in migraine patients with and without aura compared with stroke patients. A transcranial Doppler study
FJ Carod-Artal
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorL Da Silveira Ribeiro
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorH Braga
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorW Kummer
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorHM Mesquita
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorAP Vargas
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorFJ Carod-Artal
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorL Da Silveira Ribeiro
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorH Braga
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorW Kummer
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorHM Mesquita
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorAP Vargas
Department of Neurology, The Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brazilia DF, Brazil
Search for more papers by this authorAbstract
The aim of this study was to investigate the prevalence of patent foramen ovale (PFO) in a consecutive unselected cohort of migraine patients (with and without aura) and compare it with a group of ischaemic young and elderly stroke patients. One hundred and forty-one migraine patients were compared with 330 stroke patients (130 young patients; 200 elderly patients) selected from our hospital stroke data bank. PFO was assessed with transcranial Doppler sonography with i.v. injection of agitated saline. The prevalence of PFO was 51.7% in migraine with aura (MA) patients, 33.7% in migraine without aura (MoA) patients, 33.8% in young stroke patients and 20.5% in elderly stroke patients (P < 0.001). The prevalence of PFO in cryptogenic stroke in young and elderly stroke patients was, respectively, 41.1% and 25% (P = 0.04). The difference between MA and MoA patients was significant (odds ratio = 2.1). The prevalence of PFO in MA patients is higher than in MoA patients and in young cryptogenic stroke patients.
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