ENDOSCOPIC MANAGEMENT OF NON-VARICEAL UPPER GASTROINTESTINAL HAEMORRHAGE
Vu Kwan
* Department of Gastroenterology, Concord Hospital and † Department of Gastroenterology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Search for more papers by this authorCorresponding Author
Ian D. Norton
* Department of Gastroenterology, Concord Hospital and † Department of Gastroenterology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Dr Ian D. Norton, Department of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.Email: [email protected]Search for more papers by this authorVu Kwan
* Department of Gastroenterology, Concord Hospital and † Department of Gastroenterology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Search for more papers by this authorCorresponding Author
Ian D. Norton
* Department of Gastroenterology, Concord Hospital and † Department of Gastroenterology, Royal North Shore Hospital, Sydney, New South Wales, Australia
Dr Ian D. Norton, Department of Gastroenterology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.Email: [email protected]Search for more papers by this authorV. Kwan MB BS, FRACP; I. D. Norton MB BS, PhD, FRACP.
Abstract
Endoscopy plays a central role in the diagnosis and treatment of non-variceal upper gastrointestinal haemorrhage. Advances in endoscopic techniques, supported by an increasing body of high quality data, have rendered endoscopy the first-line diagnostic and therapeutic intervention for the patient presenting with an upper gastrointestinal haemorrhage. However, endoscopic intervention must be considered in the context of the overall management of the bleeding patient, often with significant comorbidities. Although parameters such as hospitalization duration, transfusion requirements and surgery rates have improved with advances in endoscopic therapy, mortality rates remain relatively static. This review addresses the current status of endoscopic intervention for non-variceal upper gastrointestinal haemorrhage. Additionally, an overview of important periprocedural management issues is presented.
References
- 1 Czernichow P, Hochain P, Nousbaum JB et al. Epidemiology and course of acute upper gastro-intestinal haemorrhage in four French geographical areas. Eur. J. Gastroenterol. Hepatol. 2000; 12: 175–81.
- 2 Silverstein FE, Gilbert DA, Tedesco FJ, Buenger NK, Persing J. The national ASGE survey on upper gastrointestinal bleeding. II. Clinical prognostic factors. Gastrointest. Endosc. 1981; 27: 80–93.
- 3
Jensen DM,
Machiacado GA.
Endoscopic hemostasis of ulcer hemorrhage with injection, thermal and combination methods.
Tech. Gastrointest. Endosc. 2005; 7: 124–31.
10.1016/j.tgie.2005.04.009 Google Scholar
- 4 Jensen D, Mawas I, Lousuebsakul V. Changes in the prevalence of different diagnoses for UGI hemorrhage in the last two decades. Gastrointest. Endosc. 2003; 57: AB47–M1796.
- 5 Xia HH, Phung N, Altiparmak E, Berry A, Matheson M, Talley NJ. Reduction of peptic ulcer disease and Helicobacter pylori infection but increase of reflux esophagitis in Western Sydney between 1990 and 1998. Dig. Dis. Sci. 2001; 46: 2716–23.
- 6 Swain CP, Storey DW, Bown SG et al. Nature of the bleeding vessel in recurrently bleeding gastric ulcers. Gastroenterology 1986; 90: 595–608.
- 7
Ikeda K,
Swain CP.
Future innovations and techniques: endoscopic hemostasis for UGI, non-variceal bleeding.
Tech. Gastrointest. Endosc. 2005; 7: 164–70.
10.1016/j.tgie.2005.04.015 Google Scholar
- 8 Graham DY, Schwartz JT. The spectrum of the Mallory-Weiss tear. Medicine (Baltimore) 1978; 57: 307–18.
- 9 Kovacs TOG. Mallory-Weiss tears, angiodysplasia, watermelon stomach, and Dieulafoy’s: a potpourri. Tech. Gastrointest. Endosc. 2005; 7: 139–47.
- 10
Kovacs TOG,
Jensen DM.
Endoscopic diagnosis and treatment of bleeding Mallory-Weiss tears.
Gastrointest. Endosc. Clin. N. Am. 1991; 1: 387–400.
10.1016/S1052-5157(18)30677-9 Google Scholar
- 11 Simoens M, Rutgeerts P. Non-variceal upper gastrointestinal bleeding. Best Pract. Res. Clin. Gastroenterol. 2001; 15: 121–33.
- 12 Bharucha AE, Gostout CJ, Balm RK. Clinical and endoscopic risk factors in the Mallory-Weiss syndrome. Am. J. Gastroenterol. 1997; 92: 805–8.
- 13 Miko TL, Thomazy VA. The caliber persistent artery of the stomach: a unifying approach to gastric aneurysm, Dieulafoy’s lesion, and submucosal arterial malformation. Hum. Pathol. 1988; 19: 914–21.
- 14 Goldman RL. Submucosal arterial malformation (“Aneurysm”) of the stomach with fatal hemorrhage. Gastroenterology 1964; 46: 589–94.
- 15 Veldhuyzen van Zanten SJ, Bartelsman JF, Schipper ME, Tytgat GN. Recurrent massive haematemesis from Dieulafoy vascular malformations – a review of 101 cases. Gut 1986; 27: 213–22.
- 16 Reilly HF 3rd, Al-Kawas FH. Dieulafoy’s lesion. Diagnosis and management. Dig. Dis. Sci. 1991; 36: 1702–7.
- 17 Norton ID, Petersen BT, Sorbi D, Balm RK, Alexander GL, Gostout CJ. Management and long-term prognosis of Dieulafoy lesion. Gastrointest. Endosc. 1999; 50: 762–7.
- 18 Schmulewitz N, Baillie J. Dieulafoy lesions: a review of 6 years of experience at a tertiary referral center. Am. J. Gastroenterol. 2001; 96: 1688–94.
- 19 Foutch PG. Angiodysplasia of the gastrointestinal tract. Am. J. Gastroenterol. 1993; 88: 807–18.
- 20 Shah IA. Angiodysplasia: morphologic diagnosis. Endoscopy 1988; 20: 149–51.
- 21 Esrailian E, Gralnek IM. Nonvariceal upper gastrointestinal bleeding: epidemiology and diagnosis. Gastroenterol. Clin. North Am. 2005; 34: 589–605.
- 22 Zimmerman J, Siguencia J, Tsvang E, Beeri R, Arnon R. Predictors of mortality in patients admitted to hospital for acute upper gastrointestinal hemorrhage. Scand. J. Gastroenterol. 1995; 30: 327–31.
- 23 Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet 2000; 356: 1318–21.
- 24 Farrell RJ, Alsahli M, LaMont JT. Is successful triage of patients with upper-gastrointestinal bleeding possible without endoscopy? Lancet 2000; 356: 1289–90.
- 25 Barkun A, Bardou M, Marshall JK. Nonvariceal Upper GI Bleeding Consensus Conference Group. Ann. Intern. Med. 2003; 139: 843–57.
- 26 Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut 1996; 38: 316–21.
- 27 Sanders DS, Carter MJ, Goodchap RJ, Cross SS, Gleeson DC, Lobo AJ. Prospective validation of the Rockall risk scoring system for upper GI hemorrhage in subgroups of patients with varices and peptic ulcers. Am. J. Gastroenterol. 2002; 97: 630–35.
- 28 Vreeburg EM, Terwee CB, Snel P et al. Validation of the Rockall risk scoring system in upper gastrointestinal bleeding. Gut 1999; 44: 331–5.
- 29 Dulai GS, Gralnek IM, Oei TT et al. Utilization of health care resources for low-risk patients with acute, nonvariceal upper GI hemorrhage: an historical cohort study. Gastrointest. Endosc. 2002; 55: 321–7.
- 30 Luk GD, Bynum TE, Hendrix TR. Gastric aspiration in localization of gastrointestinal hemorrhage. JAMA 1979; 241: 576–8.
- 31 Gilbert DA, Silverstein FE, Tedesco FJ, Buenger NK, Persing J. The national ASGE survey on upper gastrointestinal bleeding. III. Endoscopy in upper gastrointestinal bleeding. Gastrointest. Endosc. 1981; 27: 94–102.
- 32 Perng CL, Lin HJ, Chen CJ, Lee FY, Lee SD, Lee CH. Characteristics of patients with bleeding peptic ulcer requiring emergency endoscopy and aggressive treatment. Am. J. Gastroenterol. 1994; 89: 1811–14.
- 33 Cuellar RE, Gavaler JS, Alexander JA et al. Gastrointestinal tract hemorrhage. The value of a nasogastric aspirate. Arch. Intern. Med. 1990; 150: 1381–4.
- 34 Rockey DC. Gastrointestinal bleeding. In: M Feldman (ed.). Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 7th edn. Philadelphia: W. B. Saunders, 2002; 215.
- 35 Rockall TA, Logan RF, Devlin HB, Northfield TC. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage. Br. Med. J. 1995; 311: 222–6.
- 36 Longstreth GF. Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study. Am. J. Gastroenterol. 1995; 90: 206–10.
- 37
Matlock J,
Freeman ML.
Non-variceal upper GI hemorrhage: doorway to diagnosis.
Tech. Gastrointest. Endosc. 2005; 7: 112–17.
10.1016/j.tgie.2005.04.006 Google Scholar
- 38 Lin HJ, Lo WC, Lee FY, Perng CL, Tseng GY. A prospective randomized comparative trial showing that omeprazole prevents rebleeding in patients with bleeding peptic ulcer after successful endoscopic therapy. Arch. Intern. Med. 1998; 158: 54–8.
- 39 Goletti O, Sidoti F, Lippolis PV, De Negri F, Cavina E. Omeprazole versus ranitidine plus somatostatin in the treatment of severe gastroduodenal bleeding: a prospective, randomized, controlled trial. Ital. J. Gastroenterol. 1994; 26: 72–4.
- 40 Hasselgren G, Lind T, Lundell L et al. Continuous intravenous infusion of omeprazole in elderly patients with peptic ulcer bleeding. Results of a placebo-controlled multicenter study. Scand. J. Gastroenterol. 1997; 32: 328–33.
- 41 Lau JY, Sung JJ, Lee KK et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. N. Engl. J. Med. 2000; 343: 310–16.
- 42 Leontiadis GI, Sharma VK, Howden CW. Systematic review and meta-analysis of proton pump inhibitor therapy in peptic ulcer bleeding (Epub 2005 Jan 31). Br. Med. J. 2005; 330: 568.
- 43 Green FW Jr, Kaplan MM, Curtis LE, Levine PH. Effect of acid and pepsin on blood coagulation and platelet aggregation. A possible contributor prolonged gastroduodenal mucosal hemorrhage. Gastroenterology 1978; 74: 38–43.
- 44 Frossard JL, Spahr L, Queneau PE et al. Erythromycin intravenous bolus infusion in acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. Gastroenterology 2002; 123: 17–23.
- 45 Coffin B, Pocard M, Panis Y et al. Erythromycin improves the quality of EGD in patients with acute upper GI bleeding: a randomized controlled study. Gastrointest. Endosc. 2002; 56: 174–9.
- 46 Katon R. Complications of upper gastrointestinal endoscopy in the gastrointestinal bleeder. Dig. Dis. Sci. 1981; 26: 47S–54S.
- 47 Savides TJ, Jensen DM. Therapeutic endoscopy for nonvariceal gastrointestinal bleeding. Gastroenterol. Clin. North Am. 2000; 29: 465–87, vii.
- 48 Cipolletta L, Bianco MA, Rotondano G, Marmo R, Piscopo R. Outpatient management for low-risk nonvariceal upper GI bleeding: a randomized controlled trial. Gastrointest. Endosc. 2002; 55: 1–5.
- 49 Lee JG, Turnipseed S, Romano PS et al. Endoscopy-based triage significantly reduces hospitalization rates and costs of treating upper GI bleeding: a randomized controlled trial. Gastrointest. Endosc. 1999; 50: 755–61.
- 50 Rockall TA, Logan RF, Devlin HB, Northfield TC. Influencing the practice and outcome in acute upper gastrointestinal haemorrhage. Steering Committee of the National Audit of Acute Upper Gastrointestinal Haemorrhage. Gut 1997; 41: 606–11.
- 51 Lin HJ, Wang K, Perng CL et al. Early or delayed endoscopy for patients with peptic ulcer bleeding. A prospective randomized study. J. Clin. Gastroenterol. 1996; 22: 267–71.
- 52 Gan AH, Xu AG, Ling H et al. [Value and economic analysis of emergency endoscopy in the diagnosis and treatment of massive upper gastrointestinal hemorrhage.] Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2003; 15: 758–61. (In Chinese.)
- 53 Cooper GS, Chak A, Connors AF Jr, Harper DL, Rosenthal GE. The effectiveness of early endoscopy for upper gastrointestinal hemorrhage: a community-based analysis. Med. Care 1998; 36: 462–74.
- 54 Cooper GS, Chak A, Way LE, Hammar PJ, Harper DL, Rosenthal GE. Early endoscopy in upper gastrointestinal hemorrhage: associations with recurrent bleeding, surgery, and length of hospital stay. Gastrointest. Endosc. 1999; 49: 145–52.
- 55 Choudari C, Palmer K. Timing of endoscopy for severe peptic ulcer hemorrhage: out of hours emergency endoscopy is unnecessary. Gastroenterology 1996; 104: A55.
- 56 Lindenauer P, Roll F, Gebretsadik T, Terdima J. Endoscopy improves outcome and reduces length of stay in elderly patients with acute upper gastrointestinal bleeding: results of a state-wide population based analysis. Am. J. Gastroenterol. 1999; 116: A76.
- 57 Kodali VP, Petersen BT, Miller CA, Gostout CJ. A new jumbo-channel therapeutic gastroscope for acute upper gastrointestinal bleeding. Gastrointest. Endosc. 1997; 45: 409–11.
- 58 Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointestinal bleeding. Lancet 1974; 2: 394–7.
- 59 Laine L, Peterson WL. Bleeding peptic ulcer. N. Engl. J. Med. 1994; 331: 717–27.
- 60 Bleau BL, Gostout CJ, Sherman KE et al. Recurrent bleeding from peptic ulcer associated with adherent clot: a randomized study comparing endoscopic treatment with medical therapy. Gastrointest. Endosc. 2002; 56: 1–6.
- 61 Jensen DM, Kovacs TO, Jutabha R et al. Randomized trial of medical or endoscopic therapy to prevent recurrent ulcer hemorrhage in patients with adherent clots. Gastroenterology 2002; 123: 407–13.
- 62 Sung JJ, Chan FK, Lau JY et al. The effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots: a randomized comparison. Ann. Intern. Med. 2003; 139: 237–43.
- 63 Khuroo MS, Yattoo GN, Javid G et al. A comparison of omeprazoleand placebofor bleeding peptic ulcer. N. Engl. J. Med. 1997; 336: 1054–8.
- 64 Chung SC, Leung JW, Steele RJ, Crofts TJ, Li AK. Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial. Br. Med. J. 1988; 296: 1631–3.
- 65
Jensen DM.
Thermal probe or combination therapy for non-variceal UGI hemorrhage.
Tech. Gastrointest. Endosc. 1999; 1: 107–14.
10.1016/S1096-2883(99)80026-6 Google Scholar
- 66 Laine L, Cohen H, Brodhead J, Cantor D, Garcia F, Mosquera M. Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage. Gastroenterology 1992; 102: 314–16.
- 67 Sacks HS, Chalmers TC, Blum AL, Berrier J, Pagano D. Endoscopic hemostasis. An effective therapy for bleeding peptic ulcers. JAMA 1990; 264: 494–9.
- 68 Naveau S, Borotto E, Giraud J. Meta-analysis of endoscopic injection therapy versus thermal methods in peptic ulcer hemorrhage. Gastroenterology 1996; 110: A207.
- 69 Tekant Y, Goh P, Alexander DJ, Isaac JR, Kum CK, Ngoi SS. Combination therapy using adrenaline and heater probe to reduce rebleeding in patients with peptic ulcer haemorrhage: a prospective randomized trial. Br. J. Surg. 1995; 82: 223–6.
- 70 Lin HJ, Tseng GY, Perng CL, Lee FY, Chang FY, Lee SD. Comparison of adrenaline injection and bipolar electrocoagulation for the arrest of peptic ulcer bleeding. Gut 1999; 44: 715–19.
- 71 Chung SS, Lau JY, Sung JJ et al. Randomised comparison between adrenaline injection alone and adrenaline injection plus heat probe treatment for actively bleeding ulcers. Br. Med. J. 1997; 314: 1307–11.
- 72 Randall GM, Jensen DM, Hirabayashi K, Machicado GA. Controlled study of different sclerosing agents for coagulation of canine gut arteries. Gastroenterology 1989; 96: 1274–81.
- 73 O’Brien JR. Some effects of adrenaline and anti-adrenaline compounds on platelets in vitro and in vivo. Nature 1963; 200: 763–4.
- 74 Lai KH, Peng SN, Guo WS et al. Endoscopic injection for the treatment of bleeding ulcers: local tamponade or drug effect? Endoscopy 1994; 26: 338–41.
- 75 Park CH, Lee SJ, Park JH et al. Optimal injection volume of epinephrine for endoscopic prevention of recurrent peptic ulcer bleeding. Gastrointest. Endosc. 2004; 60: 875–80.
- 76 Johnston JH, Jensen DM, Auth D. Experimental comparison of endoscopic yttrium-aluminum-garnet laser, electrosurgery, and heater probe for canine gut arterial coagulation. Importance of compression and avoidance of erosion. Gastroenterology 1987; 92: 1101–8.
- 77 Norton ID, Wang L, Levine SA et al. In vivo characterization of colonic thermal injury caused by argon plasma coagulation. Gastrointest. Endosc. 2002; 55: 631–6.
- 78 Laine L. Determination of the optimal technique for bipolar electrocoagulation treatment. An experimental evaluation of the BICAP and Gold probes. Gastroenterology 1991; 100: 107–12.
- 79 Morris DL, Brearley S, Thompson H, Keighley MR. A comparison of the efficacy and depth of gastric wall injury with 3.2- and 2.3-mm bipolar probes in canine arterial hemorrhage. Gastrointest. Endosc. 1985; 31: 361–3.
- 80 Jensen DM. Heat probe for hemostasis of bleeding peptic ulcers: technique and results of randomized controlled trials. Gastrointest. Endosc. 1990; 36: S42–9.
- 81 Cipolletta L, Bianco MA, Rotondano G, Piscopo R, Prisco A, Garofano ML. Prospective comparison of argon plasma coagulator and heater probe in the endoscopic treatment of major peptic ulcer bleeding. Gastrointest. Endosc. 1998; 48: 191–5.
- 82 Chau CH, Siu WT, Law BK et al. Randomized controlled trial comparing epinephrine injection plus heat probe coagulation versus epinephrine injection plus argon plasma coagulation for bleeding peptic ulcers. Gastrointest. Endosc. 2003; 57: 455–61.
- 83 Havanond C, Havanond P. Argon plasma coagulation therapy for acute non-variceal upper gastrointestinal bleeding. Cochrane Database Syst. Rev. 2005; 15: CD 003791.
- 84 Calvet X, Vergara M, Brullet E, Gisbert JP, Campo R. Addition of a second endoscopic treatment following epinephrine injection improves outcome in high-risk bleeding ulcers. Gastroenterology 2004; 126: 441–50.
- 85 Lau JY, Leung JW. Injection therapy for bleeding peptic ulcers. Gastrointest. Endosc. Clin. N. Am. 1997; 7: 575–91.
- 86 Jensen DM, Kovacs TO. Randomized prospective study of bipolar coagulation alone compared to combination epinephrine injection and bipolar coagulation for the prevention of rebleeding from ulcers with non-bleeding visible vessels (Abstract 130). Gastrointest. Endosc. 2000; 51: 3576.
- 87 Hepworth CC, Kadirkamanathan SS, Gong F, Swain CP. A randomised controlled comparison of injection, thermal, and mechanical endoscopic methods of haemostasis on mesenteric vessels. Gut 1998; 42: 462–9.
- 88 Hepworth CC, Swain CP. Mechanical endoscopic methods of haemostasis for bleeding peptic ulcers: a review. Baillieres Best Pract. Res. Clin. Gastroenterol. 2000; 14: 467–76.
- 89 Park CH, Joo YE, Kim HS, Choi SK, Rew JS, Kim SJ. A prospective, randomized trial comparing mechanical methods of hemostasis plus epinephrine injection to epinephrine injection alone for bleeding peptic ulcer. Gastrointest. Endosc. 2004; 60: 173–9.
- 90 Wang K, Lin HJ, Chua RT, Perng CL, Lee SD, Lee CH. Hemostatic effects of heat probe thermocoagulation for patients with peptic ulcer bleeding: an experience of 329 patients. Zhonghua Yi Xue Za Zhi (Taipei) 1995; 55: 25–30.
- 91 Cipolletta L, Bianco MA, Marmo R et al. Endoclips versus heater probe in preventing early recurrent bleeding from peptic ulcer: a prospective and randomized trial. Gastrointest. Endosc. 2001; 53: 147–51.
- 92 Lin HJ, Hsieh YH, Tseng GY, Perng CL, Chang FY, Lee SD. A prospective, randomized trial of endoscopic hemoclip versus heater probe thermocoagulation for peptic ulcer bleeding. Am. J. Gastroenterol. 2002; 97: 2250–54.
- 93 Defreyne L, Vanlangenhove P, De Vos M et al. Embolization as a first approach with endoscopically unmanageable acute nonvariceal gastrointestinal hemorrhage. Radiology 2001; 218: 739–48.
- 94 Schenker MP, Duszak R Jr, Soulen MC et al. Upper gastrointestinal hemorrhage and transcatheter embolotherapy: clinical and technical factors impacting success and survival. J. Vasc. Interv. Radiol. 2001; 12: 1263–71.
- 95 Ripoll C, Banares R, Beceiro I et al. Comparison of transcatheter arterial embolization and surgery for treatment of bleeding peptic ulcer after endoscopic treatment failure. J. Vasc. Interv. Radiol. 2004; 15: 447–50.
- 96 Marmo R, Rotondano G, Bianco MA, Piscopo R, Prisco A, Cipolletta L. Outcome of endoscopic treatment for peptic ulcer bleeding: is a second look necessary? A meta-analysis. Gastrointest. Endosc. 2003; 57: 62–7.
- 97 Wong SK, Yu LM, Lau JY et al. Prediction of therapeutic failure after adrenaline injection plus heater probe treatment in patients with bleeding peptic ulcer. Gut 2002; 50: 322–5.
- 98 Chung IK, Kim EJ, Lee MS et al. Endoscopic factors predisposing to rebleeding following endoscopic hemostasis in bleeding peptic ulcers. Endoscopy 2001; 33: 969–75.
- 99 Lau JY, Sung JJ, Lam YH et al. Endoscopic retreatment compared with surgery in patients with recurrent bleeding after initial endoscopic control of bleeding ulcers. N. Engl. J. Med. 1999; 340: 751–6.
- 100 Chan FK, Ching JY, Hung LC et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N. Engl. J. Med. 2005; 352: 238–44.
- 101 Lee JM, Breslin NP, Fallon C, O’Morain CA. Rapid urease tests lack sensitivity in Helicobacter pylori diagnosis when peptic ulcer disease presents with bleeding. Am. J. Gastroenterol. 2000; 95: 1166–70.
- 102 Grino P, Pascual S, Such J et al. Comparison of diagnostic methods for Helicobacter pylori infection in patients with upper gastrointestinal bleeding. Scand. J. Gastroenterol. 2001; 36: 1254–8.
- 103 Colin R, Czernichow P, Baty V et al. Low sensitivity of invasive tests for the detection of Helicobacter pylori infection in patients with bleeding ulcer. Gastroenterol. Clin. Biol. 2000; 24: 31–5.
- 104
Jensen DM,
Kovacs TO,
Machiacado GA.
Prospective study of the stigmata of hemorrhage and endoscopic and medical treatment of bleeding Mallory-Weiss tears.
Gastrointest. Endosc. 1992; 38: 225.
10.1016/S0016-5107(92)70418-0 Google Scholar
- 105 Laine L. Multipolar electrocoagulation in the treatment of active upper gastrointestinal tract hemorrhage. A prospective controlled trial. N. Engl. J. Med. 1987; 316: 1613–17.
- 106 Llach J, Elizalde JI, Guevara MC et al. Endoscopic injection therapy in bleeding Mallory-Weiss syndrome: a randomized controlled trial. Gastrointest. Endosc. 2001; 54: 679–81.
- 107 Yamaguchi Y, Yamato T, Katsumi N et al. Endoscopic hemoclipping for upper GI bleeding due to Mallory-Weiss syndrome. Gastrointest. Endosc. 2001; 53: 427–30.
- 108 Park CH, Min SW, Sohn YH et al. A prospective, randomized trial of endoscopic band ligation vs. epinephrine injection for actively bleeding Mallory-Weiss syndrome. Gastrointest. Endosc. 2004; 60: 22–7.
- 109 Stark ME, Gostout CJ, Balm RK. Clinical features and endoscopic management of Dieulafoy’s disease. Gastrointest. Endosc. 1992; 38: 545–50.
- 110 Kasapidis P, Georgopoulos P, Delis V, Balatsos V, Konstantinidis A, Skandalis N. Endoscopic management and long-term follow-up of Dieulafoy’s lesions in the upper GI tract. Gastrointest. Endosc. 2002; 55: 527–31.
- 111 Abi-Hanna D, Williams SJ, Gillespie PE, Bourke MJ. Endoscopic band ligation for non-variceal non-ulcer gastrointestinal hemorrhage. Gastrointest. Endosc. 1998; 48: 510–14.
- 112 Mumtaz R, Shaukat M, Ramirez FC. Outcomes of endoscopic treatment of gastroduodenal Dieulafoy’s lesion with rubber band ligation and thermal/injection therapy. J. Clin. Gastroenterol. 2003; 36: 310–14.
- 113 Park CH, Sohn YH, Lee WS et al. The usefulness of endoscopic hemoclipping for bleeding Dieulafoy lesions. Endoscopy 2003; 35: 388–92.
- 114 Trudel JL, Fazio VW, Sivak MV. Colonoscopic diagnosis and treatment of arteriovenous malformations in chronic lower gastrointestinal bleeding. Clinical accuracy and efficacy. Dis. Colon Rectum 1988; 31: 107–10.
- 115 Kwan V, Bourke MJ, Williams SJ et al. Argon plasma coagulation in the management of symptomatic gastrointestinal vascular lesions: experience in 100 consecutive patients with long-term follow-up. Am. J. Gastroenterol. 2006; 101: 58–63.
- 116 Watson JP, Bennett MK, Griffin SM, Matthewson K. The tissue effect of argon plasma coagulation on esophageal and gastric mucosa. Gastrointest. Endosc. 2000; 52: 342–5.