Volume 10, Issue 3 pp. 113-124
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IMMUNOBIOLOGY OF CHILDHOOD DISEASES

DAVID G. JOSE

Corresponding Author

DAVID G. JOSE

The Royal Children's Hospital Research Foundation, Melbourne

Immunology Research Fellow, N.H. & M.R.C.

Dr. David Jose, Research Foundation, The Royal Children's Hospital, Melbourne, 3052.Search for more papers by this author

SYNOPSIS

A large part of clinical paediatrics deals with infectious disease, inflammatory conditions, allergy, auto-immune disease and cancer. The immune system plays a critical role in these diseases and in addition presents a perplexing number of conditions arising from defects in the immune system itself. This review seeks to highlight immune mechanisms in selected diseases of children and to explore the clinical value of these mechanisms in terms of diagnostic or therapeutic application. Some of the principles and mechanisms involved in immune defence have been previously considered (Jose, 1973).

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