Quantitative genetic variation and selection of enzyme activities in Drosophila melanogaster
M. Milošević
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Search for more papers by this authorCorresponding Author
N. Tucić
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Institute of Zoology, Faculty of Science, University of Bel-grade, Studentski trg 16, YU-11000 Belgrade, YugoslaviaSearch for more papers by this authorD. Marinković
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Search for more papers by this authorM. Milošević
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Search for more papers by this authorCorresponding Author
N. Tucić
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Institute of Zoology, Faculty of Science, University of Bel-grade, Studentski trg 16, YU-11000 Belgrade, YugoslaviaSearch for more papers by this authorD. Marinković
Faculty of Science and Institute for Biological Research, University of Belgrade, Belgrade, Yugoslavia
Search for more papers by this authorAbstract
The nature of the genetic variation for the activity of three enzymes (α-GPD, ME, and SOD) was studied by means of analyses of variance among full-sib and half-sib families. The results presented here indicate that the genetic variation of activity of these enzymes consist primarily of non-additive genetic variance. A moderate level of additive genetic variation was found only for α-GPD activity. We also examined the question whether an association exists between enzyme activities and selection for preadult developmental time. Using the method developed by Lande and Arnold (1983), significant directional selection was observed for α-GPD activity.
Literature
- Arnold, S. J.; Wade, M. J., 1984 a: On the measurement of natural and sexual selection: Theory. Evolution 38, 709–719.
- Arnold, S. J.; Wade, M. J. 1984 b: On the measurement of natural and sexual selection: Applications. Evolution 38, 720–734.
- Avise, C. J.; McDonald, J. F., 1976: Enzyme changes during development of holometabolic and hemimetabolic insects. Comp. Biochem. Physiol. 53, 393–397.
- Becker, W. A., 1967: Manual of Procedures in Quantitative Genetics. Washington : Washington State Univ. Press.
- Bulmer, M., 1980: Mathematical Theory of Quantitative Genetics. Oxford : Clarendon Press.
- Crow, J. F.; Nagylaki, T., 1976: The rate of change of a character correlated with fitness. Amer. Nat. 110, 207–213.
- Endler, J. A., 1986: Natural Selection in the Wild. Princeton : Princeton Univ. Press.
- Falconer, D. S., 1981: Introduction to quantitative Genetics. London and New York : Longman.
- Graf, J. D.; Ayala, F. J., 1986: Genetic variation for superoxide dismutase level in Drosophila melanogaster. Biochem. Genet. 24, 153–168.
- Lande, R., 1979: Quantitative genetic analysis of multivariate evolution, applied to brain-body size allometry. Evolution 33, 402–416.
- Lande, R.; Arnold, S. J., 1983: The measurement of selection on correlated characters. Evolution 37, 1210–1226.
- Laurie-Ahlberg, C. C.; Marini, G.; Bewley, G. C.; Luchesi, J. C.; Weir, B. C., 1980: Quantitative genetic variation of enzyme activities in natural populations of Drosophila melanogaster. Proc. Nat. Acad. Sci. 77, 1073–1077.
- Laurie-Ahlberg, C. C.; Williamson, J. H.; Cochrane, B. J.; Wilton, A. N.; Chasolow, F. I., 1981: Autosomal factors with correlated effects on the activities of the glucose-6-phosphate and 6-phosphogluconate dehydrogenase in Drosophila melanogaster. Genetics 94, 127–150.
- Laurie-Ahlberg, C. C.; Wilton, A. N.; Curtsinger, J. W.; Emigh, T. H., 1982: Naturally occurring enzyme variation in Drosophila melanogaster. I. Sources of variation for 23 enzymes. Genetics 102, 191–206.
- Lewontin, R. C., 1965: Selection for colonizing ability. In: The Genetics of Colonizing Species, 77–91. Ed. by H. G. Baker and G. L. Stebbins. New York . Academic Press.
- Lowry, D. H.; Rosebrough, N. J.; Farr, A. L.; Randal, R. J., 1951: Protein measurements with folin-phenol reagent. J. Biol. Chem. 193, 265–275.
- Marinkovć, D.; Miloševlć, M.; Milanović, M., 1986: Enzyme activity and dynamics of Drosophila development. Genetica 70, 43–52.
- Mayr, E., 1964: Animal Species and Evolution. Cambridge : Belknap Press.
- Misra, H. P.; Fridovich, I., 1972: The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247, 3170.
- Robertson, A., 1968: The spectrum of genetic variation. In: Population Biology and Evolution. Ed. by R. C. Lewontin. Syracuse Univ. Press.
- Sokal, R. R.; Rohlf, F. J., 1981: Biometry. San Francisco : Freeman.
- Stam, L. F.; Laurie-Ahlberg, C. C., 1982: A semi automated procedure for the assay of 23 enzymes from Drosophila melanogaster. Insect Biochem. 12, 537–544.
- Tucić, N.; Cvrntović, D.; Milanović, D., 1987: The genetic variation and covariation among fitness components in Drosophila melanogaster females and males. Heredity (in press.).
- Wilton, A. N.; Laurie-Ahlberg, C. C.; Emigh, T. H.; Curtsinger, J. W., 1982: Naturally occurring enzyme activity variation in Drosophila melanogaster. II. Relationships among enzymes. Genetics 102, 207–221.
