Volume 88, Issue 1 pp. 22-30

Haemovigilance in a general university hospital: need for a more comprehensive classification and a codification of transfusion-related events

M. A. Siegenthaler

Corresponding Author

M. A. Siegenthaler

Service Régional Vaudois de Transfusion Sanguine, Lausanne, Switzerland

Correspondence: M. A. Siegenthaler, Service Régional Vaudois de Transfusion Sanguine, rue du Bugnon 27, CH-1005 Lausanne, Switzerland
E-mail: [email protected]Search for more papers by this author
P. Schneider

P. Schneider

Service Régional Vaudois de Transfusion Sanguine, Lausanne, Switzerland

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D.-H. Vu

D.-H. Vu

Service Régional Vaudois de Transfusion Sanguine, Lausanne, Switzerland

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J.-D. Tissot

J.-D. Tissot

Service Régional Vaudois de Transfusion Sanguine, Lausanne, Switzerland

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First published: 21 January 2005
Citations: 25

Abstract

Background and Objectives The purpose of this study was to analyse the transfusion-related events recorded in a general university hospital.

Materials and Methods The method we used was retrospective analysis of the data collected between 1999 and 2003.

Results The incidence of transfusion reactions (n = 394) was 4·19 per 1000 blood products distributed: 59% (n = 231) were febrile non-haemolytic transfusion reactions; 22% (n = 88) were caused by allergy; 5% (n = 21) were caused by bacterial infection; and 14% (n = 54) were classified as other reactions. Platelet concentrates gave rise to a significantly greater number of reactions than erythrocyte concentrates and fresh-frozen plasma. Transfusion errors and near-miss events were also observed and were analysed separately. A series of transfusion-related events, such as haemosiderosis, metabolic disturbances or volume overload, were not reported.

Conclusions Our experience prompts us to propose a more comprehensive classification and codification of transfusion-related events.

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