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Evidence of Autonomous Red Cell Expression of Xga Antigen in Human Bone Marrow Transplantation
Abstract
Human bone marrow transplant chimeras afford the opportunity to determine whether a red blood cell antigen is autonomously controlled. Evaluation of an Xg(a-) recipient and an Xg(a+) recipient, each transplanted with bone marrow of donors of opposite Xga types, shows that the Xga antigen is of the donor type following transplantation. This indicates that the Xga antigen is controlled by the red blood cell, and confirms earlier studies in natural chimeras.
