Volume 46, Issue 2 pp. 75-79
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Effect of ABO Group, Secretor Status and Sex on Cold Hemagglutinins in Normal Adults1

Volker E. Dube MD

Corresponding Author

Volker E. Dube MD

Department of Pathology and Laboratory Medicine, Evanston Hospital, Evanston, Ill., USA

Department of Pathology and Laboratory Medicine, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201 (USA)Search for more papers by this author
Michio Tanaka

Michio Tanaka

Department of Pathology and Laboratory Medicine, Evanston Hospital, Evanston, Ill., USA

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Joan Chmiel

Joan Chmiel

Department of Pathology and Laboratory Medicine, Evanston Hospital, Evanston, Ill., USA

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Byron Anderson

Byron Anderson

Department of Pathology and Laboratory Medicine, Evanston Hospital, Evanston, Ill., USA

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First published: February 1984
Citations: 5
1

This investigation was supported by PHS Grant No. CA 26268 awarded by the National Cancer Institute, DHHS.

Abstract

The ABO group, Lewis type and secretor status were determined in 546 normal individuals (241 male, 305 female). Their serum was tested at 4°C for agglutination of group O red blood cells; the antibody was presumed to be auto-anti-I; the results were expressed as a score. Among non-A female donors, the score was higher for secretors than nonsecretors (p<0.05). Among non-A secretors of both sexes, female donors had a higher score than male donors (p<0.05). These results suggest that the level of anti-I in the serum of normal individuals may be affected by the donor's ABO group, secretor status and sex.

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