BK virus-associated hemorrhagic cystitis in a pediatric lung transplant recipient
Okan Elidemir
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorI-Fen Chang
Department of Pharmacy, Texas Childrens’ Hospital, Houston, TX, USA
Search for more papers by this authorMarc G. Schecter
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorGeorge B. Mallory
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorOkan Elidemir
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorI-Fen Chang
Department of Pharmacy, Texas Childrens’ Hospital, Houston, TX, USA
Search for more papers by this authorMarc G. Schecter
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorGeorge B. Mallory
Department of Pediatric Pulmonology, Baylor College of Medicine, Houston, TX, USA
Search for more papers by this authorAbstract
Abstract: BKV was first postulated to be a potential pathogen in 1971 when it was isolated in the urine of a renal transplant recipient. The pathology of BKV is generally confined to the urinary tract. In renal transplant recipients, BKV has been associated with hemorrhagic cystitis, urethral stenosis, and interstitial nephritis. Reports of BKV infection in lung transplant recipients are limited to a few case reports in adult patients. A recent report revealed that up to 32% of adult lung transplant recipients may shed BKV in their urine without symptoms or renal dysfunction. To our knowledge, there are no published reports of pediatric lung transplant recipients with BKV-associated hematuria. We hereby report a case of BKV-induced hemorrhagic cystitis in a pediatric lung transplant recipient.
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