Volume 66, Issue 1 pp. 64-66

Identification of a new allele in a Sicilian individual: HLA-DPB1*0302

M.H. Sheldon

Corresponding Author

M.H. Sheldon

Dynal Biotech Ltd., Bromborough, Wirral, UK

Melanie Sheldon
R & D Department
Dynal Biotech Ltd.
11 Bassendale Road
Bromborough
Wirra CH62 3QL
UK
Fax: +44 151346 2730
e-mail: melanie.sheldon@ dynalbiotech.commelanie.sheldon@ dynalbiotech.comSearch for more papers by this author
M.P. Azzaro

M.P. Azzaro

Department of Haematology and Bone Marrow Transplantation Unit, Tissue Typing Laboratory, Ferrarotto Hospital, Catania, Italy

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D. Sayer

D. Sayer

Department of Clinical Immunology & Biochemical Genetics, Royal Perth Hospital, Perth, W. Australia

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M. Bunce

M. Bunce

Dynal Biotech Ltd., Bromborough, Wirral, UK

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G. Sortino

G. Sortino

Department of Haematology and Bone Marrow Transplantation Unit, Tissue Typing Laboratory, Ferrarotto Hospital, Catania, Italy

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First published: 27 June 2005
Citations: 3

The name DPB1*0302 was officially assigned by the WHO Nomenclature Committee in June 2004. This follows the agreed policy that, subject to the conditions stated in the most recent Nomenclature Report ( 1), names will be assigned to new sequences as they are identified. Lists of such new names will be published in the following WHO Nomenclature Report. The GenBank accession number for HLA-DPB1*0302 is AY618897.

Abstract

Abstract: We report here the identification and characterization of a novel human leucocyte antigen (HLA)-DPB1 allele that was subsequently named HLA-DPB1*0302 by the WHO Nomenclature Committee. HLA-DPB1*0302 was identified in a single Sicilian individual by a combination of sequence-specific primers, reverse line sequence-specific oligonucleotide probing and DNA sequencing-based typing. The DPB1*0302 allele is most similar to the DPB1*3101 allele, differing by a single mismatch at nucleotide position 301 (T to G).

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