Interleukin-1 in the pathogenesis of fever
S. ENDRES
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
†Medizinische Klinik Innenstadt der Universität, Ziemssenstr. 1, 8000 Munich 2, FRG
Search for more papers by this authorJ. W. M. VAN DER MEER
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
‡Department of Infectious Diseases, University Hospital Leiden, The Netherlands
Search for more papers by this authorCorresponding Author
C. A. DINARELLO
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
2 Charles A. Dinarello, Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, 750 Washington Street, Boston, MA 02111, U.S.A.Search for more papers by this authorS. ENDRES
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
†Medizinische Klinik Innenstadt der Universität, Ziemssenstr. 1, 8000 Munich 2, FRG
Search for more papers by this authorJ. W. M. VAN DER MEER
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
‡Department of Infectious Diseases, University Hospital Leiden, The Netherlands
Search for more papers by this authorCorresponding Author
C. A. DINARELLO
*Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, Boston, MA 02111, U.S.A.
2 Charles A. Dinarello, Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts University-New England Medical Center, 750 Washington Street, Boston, MA 02111, U.S.A.Search for more papers by this author
References
- 1 Aarden LA, Brunner TK, Cerottini JC et al. Revised nomenclature for antigen-nonspecific T cell proliferation and helper factors. J Immunol 1979; 13: 2928–9.
- 2 Cannon JG, Dinarello CA. The nature of interleukins. In: RA Thompson, ed. Recent advances in clinical immunology. Edinburgh : Churchill Livingstone, 1987: 45–60.
- 3 Gery I, Gershon RK, Waksman BH. Potentiation of the T-cell response to mitogens. I. The responding cell. J Exp Med 1972; 136: 128–42.
- 4 Atkins E. Pathogenesis of fever. Physiol Rev 1960; 40: 1215–24.
- 5 Kampschmidt RF, Upchurch HF. Lowering of plasma iron concentration in the rat with leukocytic extracts. Am J Physiol 1969; 216: 1287–91.
- 6 Murphy PA, Chesney J, Wood WB Jr. Further purification of rabbit leukocytic pyrogen. J Lab Clin Med 1974; 83: 310.
- 7 Moore DM, Murphy PA, Chesney PJ, Wood WB Jr. Synthesis of endogenous pyrogen by rabbit leukocytes. J Exp Med 1973; 137: 1263–74.
- 8 Bodel P. Studies on the mechanism of endogenous pyrogen production. I. Investigation of new protein synthesis in stimulated human blood leukocytes. Yale J Biol 1970; 43: 145–63.
- 9 Dinarello CA, Goldin NP, Wolff SM. Demonstration and characterisation of two distinct human leukocytic pyrogens. J Exp Med 1974; 139: 1269–81.
- 10 Dinarello CA, Renfer L, Wolff SM. Human leukocytic pyrogen: purification and development of a radioimmunoassay. Proc Natl Acad Sci USA 1977; 74: 4624–7.
- 11 Murphy PA, Simon PL, Willoughby WF. Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit macrophages. J Immunol 1980; 124: 2498–501.
- 12 Dinarello CA, Renfer L, Wolff SM. The production of antibody against human leukocytic pyrogen. J Clin Invest 1977; 60: 465–72.
- 13 Rosenwasser LJ, Dinarello CA, Rosenthal AS. Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen. J Exp Med 1979; 150: 709–14.
- 14
Dinarello CA,
Rosenwasser LJ.
Lymphocyte activating properties of human endogenous pyrogen. In: J Haddon,
L Chedid,
D Mullen,
F Spreafico, eds.
Advances in immunopharmacology.
Oxford
: Pergamon Press, 1981: 419–525.
10.1016/B978-0-08-026384-7.50050-1 Google Scholar
- 15 Sztein MB, Vogel SN, Sipe JD et al. The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen. Cell Immunol 1981; 63: 164–76.
- 16 Cebula TA, Hanson DF, Moore DM, Murphy PA. Synthesis of four endogenous pyrogens by rabbit macrophages. J Lab Clin Med 1979; 94: 95–105.
- 17 Gordon H, Parker ID. A pyrogen derived from human white cells which is active in mice. Br J Exp Pathol 1980; 61: 534–9.
- 18 Lachman LB. Purification of human interleukin-1. Fed Proc 1984; 42: 2639–43.
- 19 Dinarello CA, Bernheim HA, Cannon JG et al. Purified, 35S-met, 3H-leu-labled human monocyte interleukin-1 with endogenous pyrogen activity. Br J Rheumatol 1985; 24: 59–64.
- 20 Auron PE, Webb AC, Rosenwasser LJ et al. Nucleotide sequence of human monocyte interleukin-1 precursor cDNA. Proc Natl Acad Sci USA 1984; 81: 7907–11.
- 21 Van Damme J, De Ley M, Opdenakker G, Billiau A, De Somer P. Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1. Nature (Lond) 1985; 314: 266–8.
- 22 Lomedico PT, Gubler U, Hellman CP et al. Cloning and expression of murine interleukin-1 in Escherichia coli. Nature (Lond) 1984; 312: 458–62.
- 23 Furutani Y, Notake M, Yamayoshi M et al. Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor. Nucl Acids Res 1985; 13: 5869–82.
- 24 Gubler U, Chua AO, Stern AS et al. Recombinant human interleukin-1-alpha: purification and biological characterization. J Immunol 1986; 136: 2492–7.
- 25 Auron PE, Rosenwasser LJ, Matsushima K et al. Human and murine interleukin-1 possess sequence and structural similarities. J Mol Immunol 1985; 2: 169–77.
- 26 Rimsky L, Wakasugi H, Ferrara P et al. Purification to homogeneity and NH2-terminal amino acid sequence of a novel interleukin 1 species derived from a human B-cell line. J Immunol 1986; 136: 3303–10.
- 27 Dinarello CA. Interleukin-1. Rev Infect Dis 1984; 6: 51–95.
- 28 Dinarello CA, Cannon JG, Mier JW et al. Multiple biological activities of human recombinant interleukin-1. J Clin Invest 1986; 77: 1734–9.
- 29 Dewhirst FE, Stashenko PP, Mole JE, Tsuramachi T. Purification and partial sequence of human osteoclast activating factor. Indentity with interleukin 1 beta. J Immunol 1985; 135: 2562–8.
- 30 Beasly D, Cannon JG, Dinarello CA. Interleukin-1 (IL-1) is natriuretic. Fed Proc 1987; 46: 1234.
- 31 Caverzasio J, Rizzoli R, Dayer JM, Bonjour JP. Interleukin-1 decreases renal sodium readsorption: possible mechanism of endotoxin-induced natriuresis. Am J Physiol 1987; 252: F943–6.
- 32 Rossi V, Breviario F, Ghezzi P, Dejana E, Mantovani A. Interleukin-1 induces prostacyclin in vascular cells. Science 1985; 229: 1174–6.
- 33 Dejana E, Brevario F, Erroi A et al. Modulation of endothelial cell function by different molecular species of interleukin-1. Blood 1987; 69: 695–9.
- 34 Nachman RL, Hajjar KA, Silverstein RL, Dinarello CA. Interleukin-1 induces endothelial cell synthesis of plasminogen activator inhibitor. J Exp Med 1986; 163: 1595–600.
- 35 Dinarello CA, Ikejima T, Warner SJC, Orencole SF, Lonnemann G, Libby PL. Interleukin-1 induces interleukin-1. I. Induction of circulating interleukin-1 in rabbits in vivo and in human mononuclear cells in vitro. J Immunol 1987; 139: 1902–10.
- 36 Beutler B, Cerami A. Cachectin: more than a tumor necrosis factor. N Engl J Med 1987; 316: 379–85.
- 37 Dinarello CA, Cannon JG, Wolff SM et al. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces interleukin-1. J Exp Med 1986; 163: 1433–50.
- 38 Matsushima K, Yodoi J, Tagaya Y, Oppenheim JJ. Down-regulation of interleukin l (IL.1) receptor expression by IL 1 and fate of internalized 125I-labeled IL 1 beta in a human large granular lymphocyte cell line. J Immunol 1986; 137: 3183–8.
- 39 Killian PL, Kaffka KL, Stern AS et al. Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells. J Immunol 1986; 136: 4509–14.
- 40 Murphy MT, Richards DB, Lipton JM. Antipyretic potency of centrally administered alpha-melanocyte stimulating hormone. Science 1983; 221: 192–3.
- 41 Ikejima T, Dinarello CA, Gill DM, Wolff SM. Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome. J Clin Invest 1984; 73: 1312–20.
- 42
Dinarello CA,
Wolff SM.
Exogenous pyrogens. In: AS Milton, ed.
Pyretics and Antipyretics.
Heidelberg
: Springer-Verlag, 1982: 73–112.
10.1007/978-3-642-68569-9_4 Google Scholar
- 43 Okusawa S, Dinarello CA, Endres S et al. C5a induction of human IL-1: synergistic effect with endotoxin or interferon-gamma. J Immunol 1987, in press.
- 44 Blatteis CM, Bealer SL, Hunter WS, Llanos QJ, Ahokas RA, Mashburn TA Jr. Suppression of fever after lesions of the anteroventral third ventricle in guinea pigs. Brain Res Bull 1983; 11: 519–26.
- 45 Bernheim HA, Gilbert TM, Stitt JT. Prostaglandin E levels in third ventricular cerebrospinal fluid of rabbits during fever and changes in body temperature. J Physiol 1980; 301: 69–72.
- 46 Coceani F, Bishai I, Dinarello CA, Fitzpatrick FA. Prostaglandin E2 thromboxane B2 cerebrospinal fluid of afebrile and febrile cat. Am J Physiol 1983; 244: 785–93.
- 47 Dinarello CA, Bernheim HA. Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro. J Neurochem 1981; 37: 702–8.
- 48 Stitt JT. Prostaglandin E as the neural mediator of the febrile response. Yale J Biol Med 1986; 59: 137–49.
- 49 Flower RJ, Vane JR. Inhibition of prostaglandin synthesis in brain explains the antipyretic action of paracetamol. Nature 1972; 240: 410–1.
- 50 Kluger MJ, Ringler DH, Anver MR. Fever and survival. Science 1980; 166: 166–8.
- 51 Mackowiak PA. Direct effects of hyperthermia on pathogenic microorganisms: teleologic implications with regard to fever. Rev Infect Dis 1981; 3: 508–20.
- 52 Hanson DF, Murphy PA, Silicano R, Shin HS. The effect of temperature on the activation of thymocytes by interleukins I and II. J Immunol 1983; 130: 216–21.
- 53 Lonnemann G, Bingel M, Koch KM, Shaldon S, Dinarello CA. Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes. Lymphokine Res 1987; 6: 63–9.
- 54 Cannon JG, Dinarello CA. Endogenous pyrogen activity in human plasma after exercise. Science 1983; 220: 617–9.
- 55 Wood DD, Ihrie EJ, Dinarello CA, Cohen PL. Isolation of an interleukin-1-like factor from human joint effusions. Arthritis Rheum 1983; 26: 975–83.
- 56 Pollack S, Micali A, Kinne DW et al. Endotoxin-induced in vitro release of interleukin-1 by cancer patients' monocytes: relation to stage of disease. Int J Cancer 1983; 32: 733–6.
- 57 Sandberg CI, Berman MA, Andrews BS, –riou GJ. Interleukin-1 production by mononuclear cells from patients with scleroderma. Clin Exp Immunol 1985: 59–62.
- 58 Endres S, Lonnemann G, Van der Meer JWM et al. Use of a highly sensitive radioimmunoassay for measuring intraindividual variation of human monocyte interleukin 1 beta production. Immunobiology 1987; 175: 48.
- 59 Lonnemann G, Endres S, Van der Meer JWM, Ikejima T, Cannon JG, Dinarello CA. Development and use of a highly sensitive radioimmunoassay for human interleukin-1 alpha: comparison of immunoreactive IL-1 alpha and IL-1 beta production from stimulated human mononuclear cells. Immunobiology 1987; 175: 81.
- 60
Scuderi P,
Sterling KE,
Lam KS et al.
Raised serum levels of tumour necrosis factor in parasitic infections.
Lancet
1986; ii: 1364.
10.1016/S0140-6736(86)92007-6 Google Scholar
- 61 Van der Meer JWM, Endres S, Lonnemann G et al. Concentrations of immunoreactive human tumour necrosis factor alpha produced by human mononuclear cells in vitro. J Leukocyte Biol 1987, in press.
- 62 Numerof RP, Dinarello CA, Endres S, Lonnemann G, Van der Meer JWM, Mier JW. Interleukin-2 (IL-2) stimulates the production of interleukin-1 beta (IL-1 beta), interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor (TNF alpha) from human peripheral blood mononuclear cells (MNC). Immunobiology 1987; 175: 117.
- 63 Beck A, Van der Meer JWM, Yankelev S, Dinarello CA. Immunoreactive and biological identity between interleukin-1 and hemopoietin-1. J Leucocyte Biol 1987, in press.
- 64 White CW, Ghezzi P, Dinarello CA, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin-1 pretreatment decreases lung oxidized glutathione accumulation, lung injury and mortality in rats exposed to hyperoxia. J Clin Invest 1987; 79: 1868–73.
- 65 Neta R, Douches S, Oppenheim JJ. Interleukin-1 is a radioprotector. J Immunol 1986; 136: 2483–5.
- 66 Van der Meer JWM, Barza M, Dinarello CA. Low dose recombinant interleukin-1 beta prevents septic death in neutropenic mice. Program and abstracts of the twenty-seventh interscience conference on antimicrobial agents and chemotherapy. 1987, in press.