LEF-1 expression in basal cell carcinomas
L. Kriegl
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorD. Horst
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorT. Kirchner
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorA. Jung
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorL. Kriegl
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorD. Horst
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorT. Kirchner
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorA. Jung
Institute of Pathology, Ludwig-Maximilians University of Munich, 80337 Munich, Germany
Search for more papers by this authorConflicts of interest: none declared.

References
- 1 Gerdes MJ, Yuspa SH. The contribution of epidermal stem cells to skin cancer. Stem Cell Rev 2005; 1: 225–31.
- 2 El-Bahrawy M, El-Masry N, Alison M et al. Expression of beta-catenin in basal cell carcinoma. Br J Dermatol 2003; 148: 964–70.
- 3 Saldanha G, Ghura V, Potter L et al. Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation. Br J Dermatol 2004; 151: 157–64.
- 4 Yamazaki F, Aragane Y, Kawada A et al. Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma. Br J Dermatol 2001; 145: 771–7.
- 5 Van Genderen C, Okamura RM, Farinas I et al. Development of several organs that require inductive epithelial–mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 1994; 8: 2691–703.
- 6 Niemann C, Owens DM, Hulsken J et al. Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 2002; 129: 95–109.
- 7 Nguyen A, Rosner A, Milovanovic T et al. Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression. Int J Oncol 2005; 27: 949–56.
- 8 Rivat C, Le Floch N, Sabbah M et al. Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion. FASEB J 2003; 17: 1721–3.
- 9 Kim K, Lu Z, Hay ED. Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT. Cell Biol Int 2002; 26: 463–76.
- 10 Pizarro A. E-cadherin expression is frequently reduced in infiltrative basal cell carcinoma. J Dermatol 2000; 27: 804–5.