In a single patient with severe essential acquired cold urticaria, the following drug regimes were assessed: diphenhydramine, cyproheptadine, hydroxyzine, terbutaline, cimetidine, hydroxyzine plus cimetidine, and hydroxyzine plus terbutaline.

Each regime showed favourable results, but a significance level of P - 0.01 was reached only for (a) hydroxyzine plus cimetidine in the suppression of erythema, and (b) the histamine H₁ antagonists in the suppression of wealing.

References

Bardhan, K.D., Blum, A., Gillespie, G., Larkworthy, W., Mekel, R., Moshal, M. Smith., P.M., Venables C. W., Van Tongeren, J.H.M. & Walan, A. (1977) Long-term treatment cimetidine in duodenal ulceration. Lancet, i, 900.
10.1016/S0140-6736(77)91219-3
Google Scholar
Bentley-Philips, C.B., Black, A.K. & Greves, M.W. (1976) Induced tolerance in cold urticaria caused by cold-evoked histamine release. Lancet, ii, 63.
10.1016/S0140-6736(76)92285-6
Google Scholar
Doeglas, H.M.G. (1975) Reactions to aspirin food additives in patients with chronic utricaria, including the physical urticarias. British Journal of Dermatology, 93, 135.
10.1111/j.1365-2133.1975.tb06732.x
PubMed Web of Science® Google Scholar
Douglas, W.W. (1975) Histamine and antihistamines; 5-hydroxytryptamine and antagonists. In The pharmacological Basis of therapeutics (Ed by L.S. Goodman and A. Gilman), 5th edn, p. 623. Macmillan, New York .
Google Scholar
Duncan, D.B. (1995) Multiple range and multiple P tests. Biometrics, II, 1.
Google Scholar
Dunnett, C.W. (1995) A multiple comparisons procedure for comparing several treatments with a control. Journal of the American Statistical Association, 50, 1095.
Google Scholar
Feinbberg A.R., Pruzansky J.J., Feinberg, S.M. & Fisherman, E.W. (1958) Hydroxyzine in chronic utricaria and in allergic manifestations. Journal of Allergy, 29, 358.
10.1016/0021-8707(58)90041-8
PubMed Web of Science® Google Scholar
Greaves, M.W. (1978) H₂-receptor antagonists and delayed hypersensitivity. Lancet, i, 880.
10.1016/S0140-6736(78)90228-3
Google Scholar
Illig, L. (1973) Physical utricaria. Its diagnosis and treatment. In: Current Problems in Dermatology (Ed. by J.W.H. Mali), Vol. 5, p. 79. Karger, Basel .
Google Scholar
Kaplan, A.P., Gray, L., Shaff, R.E., Horakova, Z. & Beaven, M.A. (1975) In vivo studies of mediator release in cold utricaria and cholinergic utricaria. Journal of Allergy and clinical Immunology, 55, 394.
10.1016/0091-6749(75)90078-0
PubMed Web of Science® Google Scholar
Kennes, B., De Maubeuge, J. & Delespesse, G. (1977) Treatment of chronic utricaria with a beta₂-adrenergic stimulant. Clinical Allergy, 7, 35.
10.1111/j.1365-2222.1977.tb01422.x
CAS PubMed Web of Science® Google Scholar
Lichtenstein, L.M. & Gillespie, E. (1975) The effects of the H₁ and H₂ antihistamines on ‘allergic’ histamine release and its inhibition by histamine. Journal of Pharmacology, and Experimental Therapeutics, 192, 441.
CAS PubMed Web of Science® Google Scholar
Marks, R. & Greaves, M.W. (1977) Vascular reactions to histamine and compound 48.80 in human skin: suppression by a histamine H₂-receptor blacking agent. British Journal of Clinical Pharmacology, 4, 367.
10.1111/j.1365-2125.1977.tb00725.x
CAS PubMed Web of Science® Google Scholar
Soter, N.A., Wasserman, S.I & Austen, K.F. (1976) Cold utricaria: release into the circulation of histamine and cosinophilic chemotactic factor of anaphylaxis during cold challenge. New England Journal of Medicine, 294, 687.
10.1056/NEJM197603252941302
CAS PubMed Web of Science® Google Scholar
Wallace, W.A., Orr, C.M.E. & Bearn, A.R. (1977) Perforation of chronic peptic ulcers after cimetidine. British Medical Journal, ii, 865.
10.1136/bmj.2.6091.865
Google Scholar
Wanderer, A.A., St Pherre, J.P & Ellis, E.F. (1977) Primary acquired cold urticaria. Archives of Dermatology, 113, 1375.
CAS PubMed Web of Science® Google Scholar
Warin, R.P. & Champion, R.H. (1974) Urticaria, p. 149. Saunders, London .
Google Scholar

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Volume101, Issue1

July 1979

Pages 51-55

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